20366-57-8

Basic information

• Product Name: 1-BROMONAPHTHALENE-5-ACETIC ACID METHYL ESTER
• Synonyms: 1-BROMONAPHTHALENE-5-ACETIC ACID METHYL ESTER;(5-BROMO-1-NAPHTHYL)METHANOL
• CAS NO: 20366-57-8
• Molecular Formula: C₁₁H₉BrO
• Molecular Weight: 279.12924
• EINECS: -0
• Mol File: 20366-57-8.mol
• Article Data: 8

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-BROMONAPHTHALENE-5-ACETIC ACID METHYL ESTER(CAS DataBase Reference)
• NIST Chemistry Reference: 1-BROMONAPHTHALENE-5-ACETIC ACID METHYL ESTER(20366-57-8)
• EPA Substance Registry System: 1-BROMONAPHTHALENE-5-ACETIC ACID METHYL ESTER(20366-57-8)

Safety Data

• Hazardous Substances Data: 20366-57-8(Hazardous Substances Data)

Upstream product

• 41498-06-0 5-bromo-1-naphthaldehyde 
• 64-17-5 ethanol 
• 59866-97-6 5-bromo-1-naphthoic acid methyl ester 
• 16726-67-3 5-bromo-1-naphthalenecarboxylic acid 

Downstream Products

• 1353556-05-4 (5-(2-methyl-4-(trifluoromethyl)phenyl)naphthalen-1-yl)methanol 
• 1353555-99-3 (5-(2-methoxy-4-(trifluoromethyl)phenyl)naphthalen-1-yl)methanol 
• 1353554-90-1 C₂₀H₁₈F₃N₃ 
• 1353556-06-5 C₃₀H₃₄F₃N₃O₄ 
• 1353554-88-7 C₂₁H₂₀F₃N₃O 
• 1353556-02-1 1,3-di-Boc-2-(2-(5-(2-methoxy-4-(trifluoromethyl)phenyl)naphthalen-1-yl)ethyl)guanidine 
• 1353556-00-9 (5-(2-methoxy-4-(trifluoromethyl)phenyl)naphthalen-1-yl)methyl methanesulfonate 
• 1353554-87-6 C₂₀H₁₈F₃NO 
• 1353556-01-0 2-(5-(2-methoxy-4-(trifluoromethyl)phenyl)naphthalen-1-yl)acetonitrile 
• 1353554-86-5 C₂₀H₁₈F₃N₃O 
• 1353555-98-2 1,3,-di-Boc-2-((5-(2-methoxy-4-(trifluoromethyl)phenyl)naphthalen-1-yl)methyl)guanidine 
• 4527-60-0 5-methyl-1-naphthoic acid 
• 151109-14-7 1-bromo-5-(bromomethyl)naphthalene 
• 20366-59-0 1-bromo-5-methylnaphthalene 

Relevant articles and documents

Palladium-Catalyzed Regiospecific peri- And ortho-C-H Oxygenations of Polyaromatic Rings Mediated by Tunable Directing Groups

An efficient divergent approach of Pd-catalyzed C-H oxygenation of polyaromatic rings is described. Reversible directing groups enable regiospecific peri- and ortho-oxygenation to readily access a wide array of polyaromatic phenols without pre- and postmanipulation of directing groups. The systematic mechanistic investigation, including deuterium-labeling experiments, palladacycle trapping, and DFT calculations, reveals that the tunable ligand-assisted C-H bond cleavage played a crucial role during the reaction process.

SMALL MOLECULE INHIBITORS OF DIHYDROFOLATE REDUCTASE

The disclosure relates to compositions and methods for the treatment of fungal, bacterial, and parasitic infections and inhibition of fungal, bacterial, and parasitic growth. In particular, such compositions include dihydrofolate reductase (DHFR) inhibito

Antimicrobial activity of various 4- and 5-substituted 1-phenylnaphthalenes

Bacterial cell division occurs in conjunction with the formation of a cytokinetic Z-ring structure comprised of FtsZ subunits. Agents that can disrupt Z-ring formation have the potential, through this unique mechanism, to be effective against several of the newly emerging multi-drug resistant strains of infectious bacteria. 1- and 12-Aryl substituted benzo[c]phenanthridines have been identified as antibacterial agents that could exert their activity by disruption of Z-ring formation. Substituted 4- and 5-amino-1-phenylnaphthalenes represent substructures within the pharmacophore of these benzo[c] phenanthridines. Several 4- and 5-substituted 1-phenylnaphthalenes were synthesized and evaluated for antibacterial activity against Staphylococcus aureus and Enterococcus faecalis. The impact of select compounds on the polymerization dynamics of S. aureus FtsZ was also assessed.