4,6-bis(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole

Base Information

Chemical Name:4,6-bis(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole
CAS No.:1403589-41-2
Molecular Formula:C₄₄H₃₁N₃O₉
Molecular Weight:745.745
Hs Code.:

Synonyms:4,6-bis(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole

Suppliers and Price of 4,6-bis(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4,6-bis(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4,6-bis(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole

There total 8 articles about 4,6-bis(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 1403589-27-4
6-chloro-4-(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole

: 118486-94-5
2-(tributylstannyl)furan

: 1403589-41-2
4,6-bis(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole

Guidance literature:: With palladium diacetate; potassium carbonate; XPhos; In N,N-dimethyl-formamide; at 95 ℃; for 3h;
DOI:10.1016/j.bmc.2012.08.021

Reference yield: 75.0%

: 55552-70-0
furan-3-boronic acid

: 1403589-27-4
6-chloro-4-(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole

: 1403589-41-2
4,6-bis(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole

Guidance literature:: With dihydroxyborane; palladium diacetate; potassium carbonate; XPhos; In N,N-dimethyl-formamide; at 95 ℃; for 1h;
DOI:10.1016/j.bmc.2012.08.021

Reference yield:

: 62567-91-3
ethyl 2-(5-chloro-2-nitrophenyl)-2-cyanoacetate

: 1403589-41-2
4,6-bis(furan-2-yl)-9-(2,3,5-tri-O-benzoyl-β-d-ribofuranosyl)-9H-pyrimido[4,5-b]indole

Guidance literature:: Multi-step reaction with 6 steps

1.1: acetic acid; zinc / 2.5 h / 55 °C

2.1: 190 °C

3.1: trichlorophosphate / 120 °C

4.1: N,O-bis-(trimethylsilyl)-acetamide / acetonitrile / 0.17 h / 20 °C

4.2: 8 h / Heating

5.1: bis-triphenylphosphine-palladium(II) chloride / N,N-dimethyl-formamide / 100 °C

6.1: palladium diacetate; potassium carbonate; XPhos / N,N-dimethyl-formamide / 3 h / 95 °C

With bis-triphenylphosphine-palladium(II) chloride; N,O-bis-(trimethylsilyl)-acetamide; palladium diacetate; potassium carbonate; acetic acid; zinc; XPhos; trichlorophosphate; In N,N-dimethyl-formamide; acetonitrile; 5.1: |Stille Cross Coupling;
DOI:10.1016/j.bmc.2012.08.021