methyl 2-((4-bromobenzyl)oxy)-2-methyl-3-(methylamino)-3-oxopropanoate

Base Information

Chemical Name:methyl 2-((4-bromobenzyl)oxy)-2-methyl-3-(methylamino)-3-oxopropanoate
CAS No.:1219005-45-4
Molecular Formula:C₁₃H₁₆BrNO₄
Molecular Weight:330.178
Hs Code.:

Synonyms:methyl 2-((4-bromobenzyl)oxy)-2-methyl-3-(methylamino)-3-oxopropanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of methyl 2-((4-bromobenzyl)oxy)-2-methyl-3-(methylamino)-3-oxopropanoate

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Technology Process of methyl 2-((4-bromobenzyl)oxy)-2-methyl-3-(methylamino)-3-oxopropanoate

There total 1 articles about methyl 2-((4-bromobenzyl)oxy)-2-methyl-3-(methylamino)-3-oxopropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

: 1219005-44-3
2-((4-bromobenzyl)oxy)-3-methoxy-2-methyl-3-oxopropanoic acid

: 593-51-1
methylamine hydrochloride

: 1219005-45-4
methyl 2-((4-bromobenzyl)oxy)-2-methyl-3-(methylamino)-3-oxopropanoate

Guidance literature:: With N-ethyl-N,N-diisopropylamine; HATU; In dichloromethane; N,N-dimethyl-formamide; at 0 - 25 ℃; Inert atmosphere;

Reference yield:

: 1219005-45-4
methyl 2-((4-bromobenzyl)oxy)-2-methyl-3-(methylamino)-3-oxopropanoate

: 73183-34-3
bis(pinacol)diborane

: 1219005-46-5
methyl 2-methyl-3-(methylamino)-3-oxo-2-((4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)benzyl)oxy)propanoate

Guidance literature:: With potassium acetate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH₂Cl₂; In 1,4-dioxane; for 3h; Inert atmosphere; Reflux;