Propanedinitrile, ((4-methoxyphenyl)hydrazono)-

Base Information

• Chemical Name: Propanedinitrile, ((4-methoxyphenyl)hydrazono)-
• CAS No.: 1209-14-9
• Molecular Formula: C10H8 N4 O
• Molecular Weight: 200.2
• DSSTox Substance ID: DTXSID70153057
• Nikkaji Number: J367.078C
• ChEMBL ID: CHEMBL77825
• Mol file: 1209-14-9.mol

Synonyms:1209-14-9;Propanedinitrile, ((4-methoxyphenyl)hydrazono)-;BRN 1842409;Mesoxalonitrile, (p-methoxyphenyl)hydrazone;Propanedinitrile, 2-[2-(4-methoxyphenyl)hydrazinylidene]-;((4-Methoxyphenyl)hydrazono)propanedinitrile;2-[(4-methoxyphenyl)hydrazinylidene]propanedinitrile;1-CYANO-N-(4-METHOXYPHENYL)METHANECARBOHYDRAZONOYL CYANIDE;2-[(4-methoxyphenyl)hydrazono]malononitrile;4-15-00-01330 (Beilstein Handbook Reference);CHEMBL77825;DTXSID70153057;STK054058;AKOS000486691;LS-120026;[2-(4-Methoxyphenyl)hydrazono]malononitrile;CS-0334992;2-[(4-methoxyphenyl)hydrazono] malononitrile;N-(4-methoxyphenyl)carbonohydrazonoyl dicyanide;AN-329/33310020;[2-(4-methoxyphenyl)hydrazinylidene]propanedinitrile

Chemical Property of Propanedinitrile, ((4-methoxyphenyl)hydrazono)-

Chemical Property:

• Vapor Pressure: 0.000149mmHg at 25°C
• Boiling Point: 332.1°C at 760 mmHg
• Flash Point: 154.7°C
• Density: 1.15g/cm³
• XLogP3: 2.5
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 5
• Rotatable Bond Count: 3
• Exact Mass: 200.06981089
• Heavy Atom Count: 15
• Complexity: 306

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)NN=C(C#N)C#N

Technology Process of Propanedinitrile, ((4-methoxyphenyl)hydrazono)-

There total 9 articles about Propanedinitrile, ((4-methoxyphenyl)hydrazono)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-methoxybenzenediazonium tetrafluoroborate (459-64-3) + malononitrile (109-77-3) → 2-[2-(4-methoxyphenyl)hydrazono]malononitrile (1209-14-9)

Guidance literature:

With sodium acetate; silica gel; In neat (no solvent); at 20 ℃; for 0.333333h; Milling;

DOI:10.2174/1570178611999140404111411

Reference yield: 93.0%

para-methoxyphenyldiazonium chloride (4346-59-2) + malononitrile (109-77-3) → 2-[2-(4-methoxyphenyl)hydrazono]malononitrile (1209-14-9)

Guidance literature:

With sodium acetate; In ethanol; water; at 0 - 5 ℃;

DOI:10.1007/PL00010201

Reference yield: 92.0%

4-methoxy-aniline (104-94-9) + malononitrile (109-77-3) → 2-[2-(4-methoxyphenyl)hydrazono]malononitrile (1209-14-9)

Guidance literature:

With tert.-butylnitrite; In acetonitrile; at 20 ℃; Flow reactor;

DOI:10.1002/chem.201402074

upstream raw materials:

N-(4-methoxy-phenyl)-N'-p-tolyl-triazene

ethenetetracarbonitrile

1,3-bis(4-methoxyphenyl)triazene

p-toluidine

Downstream raw materials:

2-(p-anisylhydrazono)-2-cyan-N,N-(3-oxopentamethylen)-acetamidin

4-(4-Methoxy-phenylazo)-isoxazole-3,5-diamine

Bis-(dimethoxythiophosphoryl)-monosulfan

2-(4-methoxyphenyl)hydrazono-2-thiocarbamoylacetamide