Technology Process of methyl 14,15-epoxyeicosa-cis-5,8,11-trienoate
There total 4 articles about methyl 14,15-epoxyeicosa-cis-5,8,11-trienoate which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Peroxyarachidonsaeure;
With
1,1'-carbonyldiimidazole;
In
dichloromethane;
at 20 ℃;
for 0.333333h;
Inert atmosphere;
With
urea hydrogen peroxide adduct; lithium salt of imidazole;
In
diethyl ether; dichloromethane;
at 0 ℃;
for 0.05h;
Inert atmosphere;
methanol;
Further stages;
DOI:10.1080/00397911.2014.956369
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: urea hydrogen peroxide adduct; lithium salt of imidazole / dichloromethane; diethyl ether / 0.05 h / 0 °C / Inert atmosphere
1.2: 0.05 h / Inert atmosphere
2.1: 1,1'-carbonyldiimidazole / dichloromethane / 0.33 h / 20 °C / Inert atmosphere
2.2: 0.05 h / 0 °C / Inert atmosphere
With
urea hydrogen peroxide adduct; lithium salt of imidazole; 1,1'-carbonyldiimidazole;
In
diethyl ether; dichloromethane;
DOI:10.1080/00397911.2014.956369
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: dichloromethane / 0.33 h / 20 °C / Inert atmosphere
2.1: urea hydrogen peroxide adduct; lithium salt of imidazole / dichloromethane; diethyl ether / 0.05 h / 0 °C / Inert atmosphere
2.2: 0.05 h / Inert atmosphere
3.1: 1,1'-carbonyldiimidazole / dichloromethane / 0.33 h / 20 °C / Inert atmosphere
3.2: 0.05 h / 0 °C / Inert atmosphere
With
urea hydrogen peroxide adduct; lithium salt of imidazole; 1,1'-carbonyldiimidazole;
In
diethyl ether; dichloromethane;
DOI:10.1080/00397911.2014.956369
