(1R,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-[1,3]dioxolan-2-yl-2,2,4-trimethyl-cyclohex-3-enol

Base Information

Chemical Name:(1R,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-[1,3]dioxolan-2-yl-2,2,4-trimethyl-cyclohex-3-enol
CAS No.:479541-31-6
Molecular Formula:C₁₈H₃₄O₄Si
Molecular Weight:342.551
Hs Code.:

Synonyms:(1R,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-[1,3]dioxolan-2-yl-2,2,4-trimethyl-cyclohex-3-enol

Suppliers and Price of (1R,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-[1,3]dioxolan-2-yl-2,2,4-trimethyl-cyclohex-3-enol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (1R,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-[1,3]dioxolan-2-yl-2,2,4-trimethyl-cyclohex-3-enol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (1R,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-[1,3]dioxolan-2-yl-2,2,4-trimethyl-cyclohex-3-enol

There total 5 articles about (1R,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-[1,3]dioxolan-2-yl-2,2,4-trimethyl-cyclohex-3-enol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 107-21-1
ethylene glycol

: 479541-30-5
(3S,5R)-3-(tert-Butyl-dimethyl-silanyloxy)-5-hydroxy-2,6,6-trimethyl-cyclohex-1-enecarbaldehyde

: 479541-31-6
(1R,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-[1,3]dioxolan-2-yl-2,2,4-trimethyl-cyclohex-3-enol

Guidance literature:: With pyridinium p-toluenesulfonate; In benzene; Heating;
DOI:10.1055/s-2002-32968

Reference yield:

: 18162-48-6
tert-butyldimethylsilyl chloride

: 479541-31-6
(1R,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-[1,3]dioxolan-2-yl-2,2,4-trimethyl-cyclohex-3-enol

Guidance literature:: Multi-step reaction with 3 steps

1.1: 72 percent / imidazole / dimethylformamide / 20 °C

2.1: DIBAL / toluene / -80 °C

2.2: 90 percent / MeONa / methanol / 20 °C

3.1: 71 percent / PPTS / benzene / Heating

With 1H-imidazole; pyridinium p-toluenesulfonate; diisobutylaluminium hydride; In N,N-dimethyl-formamide; toluene; benzene;
DOI:10.1055/s-2002-32968

Reference yield:

: 106036-74-2
(1S,5R)-8,8-dimethyl-2-methylene-6-oxabicyclo[3.2.1]octan-7-one

: 479541-31-6
(1R,5S)-5-(tert-Butyl-dimethyl-silanyloxy)-3-[1,3]dioxolan-2-yl-2,2,4-trimethyl-cyclohex-3-enol

Guidance literature:: Multi-step reaction with 4 steps

1.1: 85 percent / SeO₂; salicylic acid; aq. tert-BuOOH / CH₂Cl₂ / 72 h / Heating

2.1: 72 percent / imidazole / dimethylformamide / 20 °C

3.1: DIBAL / toluene / -80 °C

3.2: 90 percent / MeONa / methanol / 20 °C

4.1: 71 percent / PPTS / benzene / Heating

With 1H-imidazole; tert.-butylhydroperoxide; selenium(IV) oxide; pyridinium p-toluenesulfonate; diisobutylaluminium hydride; salicylic acid; In dichloromethane; N,N-dimethyl-formamide; toluene; benzene;
DOI:10.1055/s-2002-32968