1-[2-(2,4-dimethylphenyl)-4,5-bis(ethylsulfonyl)-3-furyl]pyridinium bromide

Base Information

• Chemical Name: 1-[2-(2,4-dimethylphenyl)-4,5-bis(ethylsulfonyl)-3-furyl]pyridinium bromide
• CAS No.: 1434568-33-8
• Molecular Formula: Br*C₂₁H₂₄NO₅S₂
• Molecular Weight: 514.461
• Mol file: 1434568-33-8.mol

Synonyms:1-[2-(2,4-dimethylphenyl)-4,5-bis(ethylsulfonyl)-3-furyl]pyridinium bromide

Chemical Property of 1-[2-(2,4-dimethylphenyl)-4,5-bis(ethylsulfonyl)-3-furyl]pyridinium bromide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-[2-(2,4-dimethylphenyl)-4,5-bis(ethylsulfonyl)-3-furyl]pyridinium bromide

There total 6 articles about 1-[2-(2,4-dimethylphenyl)-4,5-bis(ethylsulfonyl)-3-furyl]pyridinium bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 14.0%

trans-1,2-di(ethylsulfonyl)-1,2-dichloroethene (90429-52-0) + 1-(2-(2,4-dimethylphenyl)-2-oxoethyl)pyridin-1-ium bromide (59224-30-5) → [1,2-bis(ethylsulfonyl)-3-indolizinyl](2,4-dimethylphenyl)methanone (1434567-92-6) + 1-[2-(2,4-dimethylphenyl)-4,5-bis(ethylsulfonyl)-3-furyl]pyridinium bromide (1434568-33-8)

Guidance literature:

1-(2-(2,4-dimethylphenyl)-2-oxoethyl)pyridin-1-ium bromide; With triethylamine; In ethanol;

trans-1,2-di(ethylsulfonyl)-1,2-dichloroethene; In ethanol; at 50 ℃; for 0.666667h;

With hydrogen bromide; In acetic acid; at 50 - 60 ℃;

DOI:10.1016/j.tet.2013.03.098

Reference yield:

trans-1,2-di(ethylsulfonyl)-1,2-dichloroethene (90429-52-0) + 1-(2-(2,4-dimethylphenyl)-2-oxoethyl)pyridin-1-ium bromide (59224-30-5) → [1,2-bis(ethylsulfonyl)-3-indolizinyl](2,4-dimethylphenyl)methanone (1434567-92-6) + 1-[2-(2,4-dimethylphenyl)-4,5-bis(ethylsulfonyl)-3-furyl]pyridinium bromide (1434568-33-8) + 1-[2-(2,4-dimethylphenyl)-4,5-bis(ethylsulfonyl)-3-furyl]pyridinium chloride

Guidance literature:

1-(2-(2,4-dimethylphenyl)-2-oxoethyl)pyridin-1-ium bromide; With triethylamine; In ethanol;

trans-1,2-di(ethylsulfonyl)-1,2-dichloroethene; In ethanol; at 50 ℃; for 0.666667h;

DOI:10.1016/j.tet.2013.03.098

Reference yield:

2-bromo-1-(2,4-dimethylphenyl)ethanone (26346-85-0) → [1,2-bis(ethylsulfonyl)-3-indolizinyl](2,4-dimethylphenyl)methanone (1434567-92-6) + 1-[2-(2,4-dimethylphenyl)-4,5-bis(ethylsulfonyl)-3-furyl]pyridinium bromide (1434568-33-8)

Guidance literature:

Multi-step reaction with 2 steps

1.1: acetone / Reflux

2.1: triethylamine / ethanol

2.2: 0.67 h / 50 °C

2.3: 50 - 60 °C

With triethylamine; In ethanol; acetone;

DOI:10.1016/j.tet.2013.03.098

upstream raw materials:

pyridine

2-bromo-1-(2,4-dimethylphenyl)ethanone

trans-1,2-di(ethylsulfonyl)-1,2-dichloroethene

1-(2-(2,4-dimethylphenyl)-2-oxoethyl)pyridin-1-ium bromide