{2-[(5-aminomethyl-thiophene-2-carbonyl)-amino]-phenyl}carbamic acid t-butyl ester

Base Information

Chemical Name:{2-[(5-aminomethyl-thiophene-2-carbonyl)-amino]-phenyl}carbamic acid t-butyl ester
CAS No.:709665-32-7
Molecular Formula:C₁₇H₂₁N₃O₃S
Molecular Weight:347.438
Hs Code.:

Synonyms:{2-[(5-aminomethyl-thiophene-2-carbonyl)-amino]-phenyl}carbamic acid t-butyl ester

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Chemical Property of {2-[(5-aminomethyl-thiophene-2-carbonyl)-amino]-phenyl}carbamic acid t-butyl ester

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Technology Process of {2-[(5-aminomethyl-thiophene-2-carbonyl)-amino]-phenyl}carbamic acid t-butyl ester

There total 1 articles about {2-[(5-aminomethyl-thiophene-2-carbonyl)-amino]-phenyl}carbamic acid t-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 709665-29-2
{2-[(5-diallylaminomethyl-thiophene-2-carbonyl)-amino]-phenyl}carbamic acid t-butyl ester

: 709665-32-7
{2-[(5-aminomethyl-thiophene-2-carbonyl)-amino]-phenyl}carbamic acid t-butyl ester

Guidance literature:: With 1,3-dimethylbarbituric acid; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In dichloromethane; at 35 ℃; for 1h;

Reference yield:

: 709665-32-7
{2-[(5-aminomethyl-thiophene-2-carbonyl)-amino]-phenyl}carbamic acid t-butyl ester

: 105-43-1,22160-40-3
3-methylvaleric acid

: 709665-00-9
5-[(3-methyl-pentanoylamino)-methyl]-thiophene-2-carboxylic acid (2-amino-phenyl)amide

Guidance literature:: {2-[(5-aminomethyl-thiophene-2-carbonyl)-amino]-phenyl}carbamic acid t-butyl ester; 3-methylvaleric acid; With 1,1'-carbonyldiimidazole; In tetrahydrofuran; at 20 ℃; for 4h;

With trifluoroacetic acid; In tetrahydrofuran; at 20 ℃; for 2h;

Reference yield:

: 709665-32-7
{2-[(5-aminomethyl-thiophene-2-carbonyl)-amino]-phenyl}carbamic acid t-butyl ester

: 530-62-1
1,1'-carbonyldiimidazole

: 2450-71-7
Propargylamine

: 709664-04-0
5-[(3-prop-2-ynyl-ureido)-methyl]thiophene-2-carboxylic acid (2-amino-phenyl)amide

Guidance literature:: {2-[(5-aminomethyl-thiophene-2-carbonyl)-amino]-phenyl}carbamic acid t-butyl ester; 1,1'-carbonyldiimidazole; Propargylamine; In tetrahydrofuran; at 20 ℃; for 2h;

With trifluoroacetic acid; In tetrahydrofuran; at 20 ℃; for 16h;