benzoic acid N'-[cyano-(4-methoxy-phenyl)-methyl]-hydrazide

Base Information

• Chemical Name: benzoic acid N'-[cyano-(4-methoxy-phenyl)-methyl]-hydrazide
• CAS No.: 625088-16-6
• Molecular Formula: C₁₆H₁₅N₃O₂
• Molecular Weight: 281.314
• Mol file: 625088-16-6.mol

Synonyms:benzoic acid N'-[cyano-(4-methoxy-phenyl)-methyl]-hydrazide

Chemical Property of benzoic acid N'-[cyano-(4-methoxy-phenyl)-methyl]-hydrazide

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of benzoic acid N'-[cyano-(4-methoxy-phenyl)-methyl]-hydrazide

There total 1 articles about benzoic acid N'-[cyano-(4-methoxy-phenyl)-methyl]-hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

trimethylsilyl cyanide (7677-24-9) + (E)-N′-(4-methoxybenzylidene)benzohydrazide (14850-87-4) → benzoic acid N'-[cyano-(4-methoxy-phenyl)-methyl]-hydrazide (625088-16-6)

Guidance literature:

(E)-N′-(4-methoxybenzylidene)benzohydrazide; scandium tris(trifluoromethanesulfonate); In dichloromethane; at 20 ℃; for 0.25h;

trimethylsilyl cyanide; With triethylamine; In dichloromethane; at -20 ℃; for 48h;

DOI:10.1002/adsc.200505272

Reference yield:

benzoic acid N'-[cyano-(4-methoxy-phenyl)-methyl]-hydrazide (625088-16-6) → N-[5-(4-methoxy-phenyl)-3-methyl-2,4-dioxo-imidazolidin-1-yl]-benzamide

Guidance literature:

Multi-step reaction with 3 steps

1: CH₂Cl₂

2: NaOEt / ethanol

3: aq. HCl / ethanol / 20 °C

With hydrogenchloride; sodium ethanolate; In ethanol; dichloromethane;

DOI:10.1016/j.tetlet.2003.08.029

Reference yield:

benzoic acid N'-[cyano-(4-methoxy-phenyl)-methyl]-hydrazide (625088-16-6) → N-[4-imino-5-(4-methoxy-phenyl)-3-methyl-2-oxo-imidazolidin-1-yl]-benzamide

Guidance literature:

Multi-step reaction with 2 steps

1: CH₂Cl₂

2: NaOEt / ethanol

With sodium ethanolate; In ethanol; dichloromethane;

DOI:10.1016/j.tetlet.2003.08.029

upstream raw materials:

trimethylsilyl cyanide

(E)-N′-(4-methoxybenzylidene)benzohydrazide