2-allyl-2-(4-methoxyphenyl)-4-pentenenitrile

Base Information

Chemical Name:2-allyl-2-(4-methoxyphenyl)-4-pentenenitrile
CAS No.:1043416-19-8
Molecular Formula:C₁₅H₁₇NO
Molecular Weight:227.306
Hs Code.:

Synonyms:2-allyl-2-(4-methoxyphenyl)-4-pentenenitrile

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-allyl-2-(4-methoxyphenyl)-4-pentenenitrile

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Technology Process of 2-allyl-2-(4-methoxyphenyl)-4-pentenenitrile

There total 3 articles about 2-allyl-2-(4-methoxyphenyl)-4-pentenenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 91.0%

: 104-47-2
p-methoxybenzylnitrile

: 106-95-6
allyl bromide

: 1043416-19-8
2-allyl-2-(4-methoxyphenyl)-4-pentenenitrile

Guidance literature:: p-methoxybenzylnitrile; With lithium diisopropyl amide; In tetrahydrofuran; at -78 ℃; for 0.666667h;

allyl bromide; In tetrahydrofuran; at -78 - 20 ℃; for 10h;
DOI:10.1055/s-0030-1258301

Reference yield: 90.0%

: 85624-03-9
(+/-)-α-allyl-α-(p-methoxyphenyl)acetonitrile

: 106-95-6
allyl bromide

: 1043416-19-8
2-allyl-2-(4-methoxyphenyl)-4-pentenenitrile

Guidance literature:: (+/-)-α-allyl-α-(p-methoxyphenyl)acetonitrile; With lithium diisopropyl amide; In tetrahydrofuran; hexane; at -78 ℃; for 1h;

allyl bromide; at -78 - 20 ℃;
DOI:10.1039/b804081h

Reference yield: 75.0%

: 1331858-80-0
C₁₄H₁₅NO₂

: 107-18-6
allyl alcohol

: 1043416-19-8
2-allyl-2-(4-methoxyphenyl)-4-pentenenitrile

Guidance literature:: With tetrakis(triphenylphosphine) palladium⁽⁰⁾; sodium hydride; In dimethyl sulfoxide; at 60 ℃; for 12h; Inert atmosphere;
DOI:10.1021/ja205717f