2-Oxopropyl ethylene acetal N-phenylformimidate

Base Information

• Chemical Name: 2-Oxopropyl ethylene acetal N-phenylformimidate
• CAS No.: 96881-42-4
• Molecular Formula: C₁₂H₁₅NO₃
• Molecular Weight: 221.256
• Mol file: 96881-42-4.mol

Synonyms:2-Oxopropyl ethylene acetal N-phenylformimidate

Chemical Property of 2-Oxopropyl ethylene acetal N-phenylformimidate

Chemical Property:

Purity/Quality:

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Technology Process of 2-Oxopropyl ethylene acetal N-phenylformimidate

There total 1 articles about 2-Oxopropyl ethylene acetal N-phenylformimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

(2-methyl-[1,3]dioxolan-2-yl)-methanol (10004-17-8) + ethyl N-phenylformimidate (6780-49-0) → 2-Oxopropyl ethylene acetal N-phenylformimidate (96881-42-4)

Guidance literature:

With sodium; at 130 ℃; for 2h;

DOI:10.1055/s-1984-31085

Reference yield: 82.0%

2-Oxopropyl ethylene acetal N-phenylformimidate (96881-42-4) + Phenoxyacetyl chloride (701-99-5) → (3R,4R)-4-(2-Methyl-[1,3]dioxolan-2-ylmethoxy)-3-phenoxy-1-phenyl-azetidin-2-one (96855-07-1)

Guidance literature:

With triethylamine; In dichloromethane; for 12h; Ambient temperature;

DOI:10.1055/s-1984-31085

upstream raw materials:

(2-methyl-[1,3]dioxolan-2-yl)-methanol

ethyl N-phenylformimidate

Downstream raw materials:

(3R,4R)-4-(2-Methyl-[1,3]dioxolan-2-ylmethoxy)-3-phenoxy-1-phenyl-azetidin-2-one