N,N-diphenyl-2-phenylpropionamide

Base Information

• Chemical Name: N,N-diphenyl-2-phenylpropionamide
• CAS No.: 1021327-17-2
• Molecular Formula: C₂₁H₁₉NO
• Molecular Weight: 301.388
• Mol file: 1021327-17-2.mol

Synonyms:N,N-diphenyl-2-phenylpropionamide

Chemical Property of N,N-diphenyl-2-phenylpropionamide

Chemical Property:

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N-diphenyl-2-phenylpropionamide

There total 2 articles about N,N-diphenyl-2-phenylpropionamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

2-phenylpropionyl chloride (25145-43-1,36240-11-6,59981-93-0,22414-26-2) + diphenylamine (122-39-4) → N,N-diphenyl-2-phenylpropionamide (1021327-17-2)

Guidance literature:

With triethylamine; In dichloromethane; Inert atmosphere;

DOI:10.1021/acs.organomet.8b00835

Reference yield:

hydratropic acid (492-37-5,2328-24-7) + diphenylamine (122-39-4) → N,N-diphenyl-2-phenylpropionamide (1021327-17-2)

Guidance literature:

hydratropic acid; With oxalyl dichloride; N,N-dimethyl-formamide; In dichloromethane; at 0 - 20 ℃;

diphenylamine; With triethylamine; In dichloromethane; at 0 - 20 ℃; for 12h;

DOI:10.1021/acs.orglett.1c01369

Reference yield: 75.0%

Allyl acetate (591-87-7) + N,N-diphenyl-2-phenylpropionamide (1021327-17-2) → C24H23NO

Guidance literature:

With bis(η3-allyl-μ-chloropalladium(II)); C₄₀H₄₁FeN₂O₃P; lithium chloride; lithium hexamethyldisilazane; In tetrahydrofuran; at 20 ℃; optical yield given as %ee; enantioselective reaction;

DOI:10.1002/anie.200704629

upstream raw materials:

2-phenylpropionyl chloride

diphenylamine

hydratropic acid