Technology Process of rac-tert-butyl-{3-[(1E,3E,5E,7E)-3,7-dimethyldeca-1,3,5,7,9-pentaenyl]-2,4,4-trimethylcyclohex-2-enyloxy}dimethylsilane
There total 6 articles about rac-tert-butyl-{3-[(1E,3E,5E,7E)-3,7-dimethyldeca-1,3,5,7,9-pentaenyl]-2,4,4-trimethylcyclohex-2-enyloxy}dimethylsilane which
guide to synthetic route it.
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synthetic route:
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![rac-tert-butyl-{3-[(1E,3E,5E,7E)-3,7-dimethyldeca-1,3,5,7,9-pentaenyl]-2,4,4-trimethylcyclohex-2-enyloxy}dimethylsilane](/Databaselist/images/loading.webp)
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1353023-74-1
rac-tert-butyl-{3-[(1E,3E,5E,7E)-3,7-dimethyldeca-1,3,5,7,9-pentaenyl]-2,4,4-trimethylcyclohex-2-enyloxy}dimethylsilane
- Guidance literature:
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Methyltriphenylphosphonium bromide;
With
sodium hexamethyldisilazane;
In
tetrahydrofuran; hexane;
at 25 ℃;
for 0.5h;
Inert atmosphere;
rac-all-trans-4-(tert-butyldimethylsilyloxy)retinal;
With
N,N,N,N,N,N-hexamethylphosphoric triamide;
In
tetrahydrofuran; hexane;
at -78 ℃;
for 1h;
Inert atmosphere;
DOI:10.1002/ejoc.201100935
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1353023-74-1
rac-tert-butyl-{3-[(1E,3E,5E,7E)-3,7-dimethyldeca-1,3,5,7,9-pentaenyl]-2,4,4-trimethylcyclohex-2-enyloxy}dimethylsilane
- Guidance literature:
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Multi-step reaction with 3 steps
1.1: tetrakis(triphenylphosphine) palladium(0); copper(I) thiophene-2-carboxylate; Tetrabutylammoniumsalz der Diphenylphosphinsaeure / N,N-dimethyl-formamide / 2 h / 25 °C / Inert atmosphere
2.1: pyridine; Dess-Martin periodane / dichloromethane / 4 h / 0 °C / Inert atmosphere
3.1: sodium hexamethyldisilazane / tetrahydrofuran; hexane / 0.5 h / 25 °C / Inert atmosphere
3.2: 1 h / -78 °C / Inert atmosphere
With
pyridine; tetrakis(triphenylphosphine) palladium(0); copper(I) thiophene-2-carboxylate; sodium hexamethyldisilazane; Dess-Martin periodane; Tetrabutylammoniumsalz der Diphenylphosphinsaeure;
In
tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide;
1.1: Stille coupling / 3.1: Wittig reaction / 3.2: Wittig reaction;
DOI:10.1002/ejoc.201100935
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1353023-74-1
rac-tert-butyl-{3-[(1E,3E,5E,7E)-3,7-dimethyldeca-1,3,5,7,9-pentaenyl]-2,4,4-trimethylcyclohex-2-enyloxy}dimethylsilane
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: pyridine; Dess-Martin periodane / dichloromethane / 4 h / 0 °C / Inert atmosphere
2.1: sodium hexamethyldisilazane / tetrahydrofuran; hexane / 0.5 h / 25 °C / Inert atmosphere
2.2: 1 h / -78 °C / Inert atmosphere
With
pyridine; sodium hexamethyldisilazane; Dess-Martin periodane;
In
tetrahydrofuran; hexane; dichloromethane;
2.1: Wittig reaction / 2.2: Wittig reaction;
DOI:10.1002/ejoc.201100935
