CID 6857544

Base Information

• Chemical Name: CID 6857544
• CAS No.: 51-57-0
• Molecular Formula: C10H15 N . Cl H
• Molecular Weight: 185.697
• Hs Code.: 2921499090
• Mol file: 51-57-0.mol

Synonyms:

 This product is a nationally controlled contraband, and the Lookchem platform doesn't provide relevant sales information.

Chemical Property of CID 6857544

Chemical Property:

• Vapor Pressure: 0.147mmHg at 25°C
• Melting Point: 166-168oC
• Boiling Point: 215.5°Cat760mmHg
• Flash Point: 86.8°C
• PSA: 12.03000
• Density: g/cm³
• LogP: 3.02990
• Storage Temp.: Controlled Substance, -20°C Freezer
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 3
• Exact Mass: 185.0971272
• Heavy Atom Count: 12
• Complexity: 95

Purity/Quality:

Safty Information:

• Hazard Codes: T,F
• Statements: 25-39/23/24/25-23/24/25-11
• Safety Statements: 45-36/37-16

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(CC1=CC=CC=C1)[NH2+]C.[Cl-]
• Isomeric SMILES: C[C@@H](CC1=CC=CC=C1)[NH2+]C.[Cl-]
• Description: (+)-Methamphetamine (Item No. 13997) is an analytical reference material categorized as an amphetamine. It is the more physiologically active isomer of (±)-methamphetamine and is both neurotoxic and frequently abused. Methamphetamine is regulated as a Schedule II compound in the United States. This product is intended for research and forensic applications.
• Therapeutic Function: Sympathomimetic, Central stimulant

Technology Process of CID 6857544

There total 8 articles about CID 6857544 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.8%

Methamphetamin (537-46-2) + benzyl chloride (100-44-7) → benzphetamine (156-08-1) + S-methamphetamine hydrochloride (51-57-0,4298-16-2)

Guidance literature:

at 100 - 145 ℃; for 3.38333h; Product distribution / selectivity;

Reference yield: 95.0%

Methamphetamin (537-46-2) + benzyl chloride (100-44-7) → benzphetamine (156-08-1) + benzfetamine hydrochloride (5411-22-3) + S-methamphetamine hydrochloride (51-57-0,4298-16-2)

Guidance literature:

In water; toluene; at 70 - 120 ℃; for 8.16667h; Product distribution / selectivity;

Reference yield: 80.0%

Novafed (345-78-8) → S-methamphetamine hydrochloride (51-57-0,4298-16-2)

Guidance literature:

Novafed; With iodine; hypophosphorous acid; Heating;

With sodium hydroxide; In water; pH=> 10;

With hydrogenchloride; In toluene;

DOI:10.1071/CH09429

upstream raw materials:

Methamphetamin

benzyl chloride

ephedrine

Novafed

Downstream raw materials:

Phenylpropionyl-L-pervitin

[Hydroxy(4-phenylbutyl)phosphinyl]acetic acid, ethyl ester

benzfetamine hydrochloride

(S)-1-cyclohexyl-N-methylpropan-2-amine

Refernces

• 1、 Pramanik, Chinmoy,Bapat, Kiran,Chaudhari, Ashok,Kulkarni, Mukund G.,Kolla, Rangarao,Sompalli, Srinivasarao,Tripathy, Narendra K.,Gurjar, Mukund K.. "An efficient, scalable process for benzphetamine hydrochloride". . p. 495 - 500. Retrieved 2014/05/06.
• 2、 Matsumoto, Teruki,Urano, Yasuteru,Makino, Yukiko,Kikura-Hanajiri, Ruri,Kawahara, Nobuo,Goda, Yukihiro,Nagano, Tetsuo. "Evaluation of characteristic deuterium distributions of ephedrines and methamphetamines by NMR spectroscopy for drug profiling". . p. 1176 - 1181. Retrieved 2008/09/17.