(R)-1-((R)-1-phenylethyl)-2-((1S,2S)-1,2,3-tris(benzyloxy)propyl)aziridine

Base Information

Chemical Name:(R)-1-((R)-1-phenylethyl)-2-((1S,2S)-1,2,3-tris(benzyloxy)propyl)aziridine
CAS No.:1534390-95-8
Molecular Formula:C₃₄H₃₇NO₃
Molecular Weight:507.673
Hs Code.:

Synonyms:(R)-1-((R)-1-phenylethyl)-2-((1S,2S)-1,2,3-tris(benzyloxy)propyl)aziridine

Suppliers and Price of (R)-1-((R)-1-phenylethyl)-2-((1S,2S)-1,2,3-tris(benzyloxy)propyl)aziridine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-1-((R)-1-phenylethyl)-2-((1S,2S)-1,2,3-tris(benzyloxy)propyl)aziridine

Chemical Property:

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Technology Process of (R)-1-((R)-1-phenylethyl)-2-((1S,2S)-1,2,3-tris(benzyloxy)propyl)aziridine

There total 7 articles about (R)-1-((R)-1-phenylethyl)-2-((1S,2S)-1,2,3-tris(benzyloxy)propyl)aziridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₁₃H₁₉NO₃

: 100-39-0
benzyl bromide

: 1534390-95-8
(R)-1-((R)-1-phenylethyl)-2-((1S,2S)-1,2,3-tris(benzyloxy)propyl)aziridine

Guidance literature:: C₁₃H₁₉NO₃; With sodium hydride; In tetrahydrofuran; mineral oil; at 0 ℃; for 1h;

benzyl bromide; With tetra-(n-butyl)ammonium iodide; In tetrahydrofuran; mineral oil; at 20 ℃; for 12h;
DOI:10.1055/s-0033-1338545

Reference yield:

: C₁₃H₁₉NO₃

: 100-39-0
benzyl bromide

: 1534390-95-8
(R)-1-((R)-1-phenylethyl)-2-((1S,2S)-1,2,3-tris(benzyloxy)propyl)aziridine

Guidance literature:: C₁₃H₁₉NO₃; With sodium hydride; In N,N-dimethyl-formamide; mineral oil; at 0 ℃; for 0.5h;

benzyl bromide; In d₇-N,N-dimethylformamide; mineral oil; at 20 ℃; for 6h;

Reference yield:

: ethyl 2,3-dihydroxy-3-{(R)-1-[(R)-1-phenylethyl]aziridin-2-yl}propanoate

: 1534390-95-8
(R)-1-((R)-1-phenylethyl)-2-((1S,2S)-1,2,3-tris(benzyloxy)propyl)aziridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium aluminium tetrahydride / tetrahydrofuran / 0.33 h / 0 °C

2.1: sodium hydride / tetrahydrofuran; mineral oil / 1 h / 0 °C

2.2: 12 h / 20 °C

With lithium aluminium tetrahydride; sodium hydride; In tetrahydrofuran; mineral oil;
DOI:10.1055/s-0033-1338545