Acetic 5-hydroxy-2-(4-hydroxy-phenyl)-4-oxo-chroman-7-yl ester

Base Information

• Chemical Name: Acetic 5-hydroxy-2-(4-hydroxy-phenyl)-4-oxo-chroman-7-yl ester
• CAS No.: 128373-95-5
• Molecular Formula: C₁₇H₁₄O₆
• Molecular Weight: 314.295
• Mol file: 128373-95-5.mol

Synonyms:Acetic 5-hydroxy-2-(4-hydroxy-phenyl)-4-oxo-chroman-7-yl ester

Chemical Property of Acetic 5-hydroxy-2-(4-hydroxy-phenyl)-4-oxo-chroman-7-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of Acetic 5-hydroxy-2-(4-hydroxy-phenyl)-4-oxo-chroman-7-yl ester

There total 3 articles about Acetic 5-hydroxy-2-(4-hydroxy-phenyl)-4-oxo-chroman-7-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on (480-41-1) + acetic anhydride (108-24-7) → 4'-O-acetylnaringenin + Acetic 5-hydroxy-2-(4-hydroxy-phenyl)-4-oxo-chroman-7-yl ester (128373-95-5)

Guidance literature:

With diphenyl hydrogen phosphate; In ethyl acetate; at 45 ℃;

DOI:10.1021/acscatal.9b03535

Reference yield:

5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on (480-41-1) + acetic anhydride (108-24-7) → 4'-O-acetylnaringenin + Acetic 5-hydroxy-2-(4-hydroxy-phenyl)-4-oxo-chroman-7-yl ester (128373-95-5) + 2-(4-acetoxyphenyl)-5-hydroxy-4-oxochroman-7-yl acetate (3162-03-6)

Guidance literature:

With C₅₆H₅₃O₄P; In ethyl acetate; at 45 ℃; Reagent/catalyst;

DOI:10.1021/acscatal.9b03535

Reference yield:

5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on (480-41-1) + acetyl chloride (75-36-5) → 4'-O-acetylnaringenin + Acetic 5-hydroxy-2-(4-hydroxy-phenyl)-4-oxo-chroman-7-yl ester (128373-95-5) + 2-(4-acetoxyphenyl)-5-hydroxy-4-oxochroman-7-yl acetate (3162-03-6)

Guidance literature:

With potassium carbonate; In acetonitrile; at 20 ℃;

DOI:10.1021/acscatal.9b03535

upstream raw materials:

5,7-Dihydroxy-2-(4-hydroxy-phenyl)-chroman-4-on

acetic anhydride

acetyl chloride

Downstream raw materials:

Acetic acid 3,5-dihydroxy-4-[3-(4-hydroxy-phenyl)-propyl]-phenyl ester