4(1H)-Pyridazinone, 3,6-bis(chloromethyl)-

Base Information

• Chemical Name: 4(1H)-Pyridazinone, 3,6-bis(chloromethyl)-
• CAS No.: 40838-54-8
• Molecular Formula: C6H6Cl2N2O
• Molecular Weight: 0
• Hs Code.: 2933990090
• Mol file: 40838-54-8.mol

Synonyms:3,6-bis-chloromethyl-1H-pyridazin-4-one;3',6'-Bis-brommethyl-o-terphenyl;3,6-Bis-chlormethyl-1H-pyridazin-4-on;

Chemical Property of 4(1H)-Pyridazinone, 3,6-bis(chloromethyl)-

Chemical Property:

• Vapor Pressure: 0.00369mmHg at 25°C
• Boiling Point: 280.8°C at 760 mmHg
• Flash Point: 123.7°C
• PSA: 45.75000
• Density: 1.53g/cm³
• LogP: 1.24750

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4(1H)-Pyridazinone, 3,6-bis(chloromethyl)-

There total 2 articles about 4(1H)-Pyridazinone, 3,6-bis(chloromethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

NSC 166900 (17417-44-6) → 3,6-Bis-(chlormethyl)-4-oxo-1,4-dihydropyridazin (40838-54-8)

Guidance literature:

With thionyl chloride;

DOI:10.1002/hlca.19580410645

Reference yield:

→ 3,6-Bis-(chlormethyl)-4-oxo-1,4-dihydropyridazin (40838-54-8)

Guidance literature:

3,6-Bis-(hydroxymethyl)-4-oxo-1,4-dihydropyridazin 4, HCl, SOCl2;

Reference yield:

3,6-Bis-(chlormethyl)-4-oxo-1,4-dihydropyridazin (40838-54-8) → 3,6-dimethylpyridazine (1632-74-2)

Guidance literature:

Multi-step reaction with 3 steps

1: palladium/charcoal; sodium acetate; acetic acid ethanol / Hydrogenation

2: POCl₃

3: palladium/charcoal; methanol; sodium acetate / Hydrogenation

With methanol; palladium on activated charcoal; sodium acetate; acetic acid ethanol; trichlorophosphate;

DOI:10.1002/hlca.19580410645

upstream raw materials:

NSC 166900

Downstream raw materials:

3,6-dimethylpyridazine