3-(4-(2-pyridinyl)piperazinomethyl)-2-phenyl-7-ethoxyimidazo[2,1-b]benzothiazole

Base Information

• Chemical Name: 3-(4-(2-pyridinyl)piperazinomethyl)-2-phenyl-7-ethoxyimidazo[2,1-b]benzothiazole
• CAS No.: 1334950-67-2
• Molecular Formula: C₂₇H₂₇N₅OS
• Molecular Weight: 469.61

Synonyms:3-(4-(2-pyridinyl)piperazinomethyl)-2-phenyl-7-ethoxyimidazo[2,1-b]benzothiazole

Chemical Property of 3-(4-(2-pyridinyl)piperazinomethyl)-2-phenyl-7-ethoxyimidazo[2,1-b]benzothiazole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-(4-(2-pyridinyl)piperazinomethyl)-2-phenyl-7-ethoxyimidazo[2,1-b]benzothiazole

There total 3 articles about 3-(4-(2-pyridinyl)piperazinomethyl)-2-phenyl-7-ethoxyimidazo[2,1-b]benzothiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

2-phenyl-7-ethoxy-imidazo[2,1-b]benzothiazole (38956-34-2) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + 1-(2-pyridyl)piperazine (34803-66-2) → 3-(4-(2-pyridinyl)piperazinomethyl)-2-phenyl-7-ethoxyimidazo[2,1-b]benzothiazole (1334950-67-2)

Guidance literature:

With zinc(II) chloride; In ethanol; water; at 20 ℃; for 4h;

DOI:10.1016/j.ejmech.2011.06.031

Reference yield:

α-bromoacetophenone (70-11-1) → 3-(4-(2-pyridinyl)piperazinomethyl)-2-phenyl-7-ethoxyimidazo[2,1-b]benzothiazole (1334950-67-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: ethanol / 0.07 h / 100 °C / 12929 Torr / Microwave irradiation

1.2: 0.08 h / Reflux

2.1: zinc(II) chloride / ethanol; water / 4 h / 20 °C

With zinc(II) chloride; In ethanol; water; 2.1: Mannich reaction;

DOI:10.1016/j.ejmech.2011.06.031

Reference yield:

2-Amino-6-ethoxybenzothiazole (94-45-1) → 3-(4-(2-pyridinyl)piperazinomethyl)-2-phenyl-7-ethoxyimidazo[2,1-b]benzothiazole (1334950-67-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: ethanol / 0.07 h / 100 °C / 12929 Torr / Microwave irradiation

1.2: 0.08 h / Reflux

2.1: zinc(II) chloride / ethanol; water / 4 h / 20 °C

With zinc(II) chloride; In ethanol; water; 2.1: Mannich reaction;

DOI:10.1016/j.ejmech.2011.06.031

upstream raw materials:

2-phenyl-7-ethoxy-imidazo[2,1-b]benzothiazole

formaldehyd

1-(2-pyridyl)piperazine

2-Amino-6-ethoxybenzothiazole

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 1334950-67-2 3-(4-(2-pyridinyl)piperazinomethyl)-2-phenyl-7-ethoxyimidazo[2,1-b]benzothiazole

Send

Send

Metric Ton KG G Pound L ML

Send

Send