(4-Benzoylamino-benzoylamino)-acetic acid

Base Information

Chemical Name:(4-Benzoylamino-benzoylamino)-acetic acid
CAS No.:133604-60-1
Molecular Formula:C₁₆H₁₄N₂O₄
Molecular Weight:298.298
Hs Code.:
ChEMBL ID:CHEMBL302999
DSSTox Substance ID:DTXSID501298158

Synonyms:CHEMBL302999;(4-Benzoylamino-benzoylamino)-acetic acid;Oprea1_221557;DTXSID501298158;N-[4-(Benzoylamino)benzoyl]glycine;BDBM50009996;AKOS000176431;133604-60-1

Suppliers and Price of (4-Benzoylamino-benzoylamino)-acetic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (4-Benzoylamino-benzoylamino)-acetic acid

Chemical Property:

XLogP3:1.1
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:298.09535693
Heavy Atom Count:22
Complexity:410

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(=O)NC2=CC=C(C=C2)C(=O)NCC(=O)O

Technology Process of (4-Benzoylamino-benzoylamino)-acetic acid

There total 3 articles about (4-Benzoylamino-benzoylamino)-acetic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 60.0%

: 61-78-9
p-Aminohippuric acid

: 98-88-4
benzoyl chloride

: 133604-60-1
(4-Benzoylamino-benzoylamino)-acetic acid

Guidance literature:: With sodium hydrogencarbonate; In tetrahydrofuran; for 1h; Ambient temperature;
DOI:10.1021/jm00111a030

Reference yield:

: 2645-07-0
4-nitrohippuric acid

: 133604-60-1
(4-Benzoylamino-benzoylamino)-acetic acid

Guidance literature:: Multi-step reaction with 2 steps

1: H₂ / 5percent Pd-C / ethanol / 0.5 h / 2327.2 Torr

2: 60 percent / aq. NaHCO₃ / tetrahydrofuran / 1 h / Ambient temperature

With hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol;
DOI:10.1021/jm00111a030

Reference yield:

: 122-04-3
4-nitro-benzoyl chloride

: 133604-60-1
(4-Benzoylamino-benzoylamino)-acetic acid

Guidance literature:: Multi-step reaction with 3 steps

1: NaOH / H₂O / 0.5 h / Ambient temperature

2: H₂ / 5percent Pd-C / ethanol / 0.5 h / 2327.2 Torr

3: 60 percent / aq. NaHCO₃ / tetrahydrofuran / 1 h / Ambient temperature

With sodium hydroxide; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In tetrahydrofuran; ethanol; water;
DOI:10.1021/jm00111a030