2-[(1R,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole

Base Information

Chemical Name:2-[(1R,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole
CAS No.:162438-92-8
Molecular Formula:C₄₈H₄₆N₂O₅
Molecular Weight:730.904
Hs Code.:

Synonyms:2-[(1R,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole

Suppliers and Price of 2-[(1R,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of 2-[(1R,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Hazard Codes:

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Useful:

Technology Process of 2-[(1R,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole

There total 5 articles about 2-[(1R,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

: 15469-97-3
N-tritylimidazole

: 16838-89-4,17073-88-0,60933-68-8,60933-69-9,73068-66-3,89361-52-4,89615-42-9,89615-45-2,96192-07-3
2,3,5-tri-O-benzyl-α-L-ribofuranose

: 162491-51-2
2-[(1S,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole

: 162438-92-8
2-[(1R,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole

Guidance literature:: With n-butyllithium; In tetrahydrofuran; at 0 ℃; for 0.5h;
DOI:10.1016/0040-4039(94)02460-S

Reference yield: 47.0%

: 16838-89-4,17073-88-0,60933-68-8,60933-69-9,73068-66-3,89361-52-4,89615-42-9,89615-45-2,96192-07-3
2,3,5-tri-O-benzyl-α-L-ribofuranose

: C₂₂H₁₇LiN₂

: 162491-51-2
2-[(1S,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole

: 162438-92-8
2-[(1R,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole

Guidance literature:: DOI:10.7164/antibiotics.48.286

Reference yield:

: 100-39-0
benzyl bromide

: 162438-92-8
2-[(1R,2R,3S,4S)-2,3,5-tris(benzyloxy)-1,4-dihydroxypent-1-yl]-N-triphenylmethylimidazole

Guidance literature:: Multi-step reaction with 3 steps

1: NaH / dimethylformamide / 0 °C

2: 0.05N HCl / dioxane / 105 °C

3: 47 percent / 1.) nBuLi / tetrahydrofuran / 0.5 h / 0 °C

With hydrogenchloride; n-butyllithium; sodium hydride; In tetrahydrofuran; 1,4-dioxane; N,N-dimethyl-formamide;
DOI:10.1016/0040-4039(94)02460-S