Technology Process of 5-(3,5-dimethoxyphenyl)-1,3,9-trimethoxy-4-(4-methoxyphenyl)acephenanthrylene
There total 9 articles about 5-(3,5-dimethoxyphenyl)-1,3,9-trimethoxy-4-(4-methoxyphenyl)acephenanthrylene which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
iron(III) chloride hexahydrate;
In
dichloromethane;
at 20 ℃;
for 3h;
DOI:10.1021/jo301345a
- Guidance literature:
-
Multi-step reaction with 2 steps
1: toluene-4-sulfonic acid / toluene / 4 h / 20 °C
2: iron(III) chloride hexahydrate / dichloromethane / 3 h / 20 °C
With
iron(III) chloride hexahydrate; toluene-4-sulfonic acid;
In
dichloromethane; toluene;
DOI:10.1021/jo301345a
- Guidance literature:
-
Multi-step reaction with 5 steps
1: (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; N-ethyl-N,N-diisopropylamine / N,N-dimethyl-formamide / 4 h / 25 °C
2: tetrahydrofuran / 3 h / 0 - 25 °C
3: tetrahydrofuran / 3 h / 0 - 25 °C
4: toluene-4-sulfonic acid / toluene / 4 h / 20 °C
5: iron(III) chloride hexahydrate / dichloromethane / 3 h / 20 °C
With
iron(III) chloride hexahydrate; (benzotriazo-1-yloxy)tris(dimethylamino)phosphonium hexafluorophosphate; toluene-4-sulfonic acid; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene;
2: |Grignard Reaction / 3: |Grignard Reaction;
DOI:10.1021/jo301345a
