methyl 2,4,6-tri-O-benzoyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-D-galactopyranoside

Base Information

• Chemical Name: methyl 2,4,6-tri-O-benzoyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-D-galactopyranoside
• CAS No.: 98056-61-2
• Molecular Formula: C₆₂H₅₂O₁₈
• Molecular Weight: 1085.08
• Mol file: 98056-61-2.mol

Synonyms:methyl 2,4,6-tri-O-benzoyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-D-galactopyranoside

Chemical Property of methyl 2,4,6-tri-O-benzoyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 2,4,6-tri-O-benzoyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-D-galactopyranoside

There total 6 articles about methyl 2,4,6-tri-O-benzoyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

methyl 2,4,6-tri-O-benzoyl-β-D-galactopyranoside (34820-02-5) + 2,3,4,6-tetra-O-benzoyl-α-D-galactopyranosyl bromide (61198-88-7) → methyl 2,4,6-tri-O-benzoyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-D-galactopyranoside (98056-61-2)

Guidance literature:

With 2,4,6-trimethyl-pyridine; silver trifluoromethanesulfonate; In nitromethane; toluene; at -25 - -20 ℃; for 0.333333h;

DOI:10.1016/S0008-6215(00)90746-8

Reference yield:

benzyl bromide (100-39-0) → methyl 2,4,6-tri-O-benzoyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-D-galactopyranoside (98056-61-2)

Guidance literature:

Multi-step reaction with 4 steps

1: 1.) dibutyltin oxide; 2.) tetrabutylammonium iodide / 1.) PhH, reflux, 16 h

2: 95 percent / pyridine

3: H₂ / catalytic hydrogenolysis

4: silver triflate, sym-collidine / nitromethane; toluene / -25 °C

With pyridine; 2,4,6-trimethyl-pyridine; hydrogen; silver trifluoromethanesulfonate; tetra-(n-butyl)ammonium iodide; di(n-butyl)tin oxide; In nitromethane; toluene;

DOI:10.1016/0008-6215(85)85240-X

Reference yield:

methyl 3-O-benzyl-β-D-galactopyranoside (40010-11-5,61277-64-3,65942-01-0,81371-52-0,93714-01-3,108644-64-0,133268-63-0,133268-64-1,143005-10-1,143005-11-2,81371-53-1) → methyl 2,4,6-tri-O-benzoyl-3-O-(2,3,4,6-tetra-O-benzoyl-β-D-galactopyranosyl)-D-galactopyranoside (98056-61-2)

Guidance literature:

Multi-step reaction with 3 steps

1: 95 percent / pyridine

2: H₂ / catalytic hydrogenolysis

3: silver triflate, sym-collidine / nitromethane; toluene / -25 °C

With pyridine; 2,4,6-trimethyl-pyridine; hydrogen; silver trifluoromethanesulfonate; In nitromethane; toluene;

DOI:10.1016/0008-6215(85)85240-X

upstream raw materials:

methyl 2,4,6-tri-O-benzoyl-β-D-galactopyranoside

2,3,4,6-tetra-O-benzoyl-α-D-galactopyranosyl bromide

methyl 3-O-benzyl-β-D-galactopyranoside

benzyl bromide

Downstream raw materials:

methyl β-D-galactopyranosyl-<1->3>-β-D-galactopyranoside