tert-butyl N-[(2S,3S)-4-amino-3-hydroxy-1-phenylbutan-2-yl]carbamate

Base Information

Chemical Name:tert-butyl N-[(2S,3S)-4-amino-3-hydroxy-1-phenylbutan-2-yl]carbamate
CAS No.:162541-34-6
Molecular Formula:C₁₅H₂₄N₂O₃
Molecular Weight:280.367
Hs Code.:

Synonyms:SCHEMBL1602032

Suppliers and Price of tert-butyl N-[(2S,3S)-4-amino-3-hydroxy-1-phenylbutan-2-yl]carbamate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of tert-butyl N-[(2S,3S)-4-amino-3-hydroxy-1-phenylbutan-2-yl]carbamate

Chemical Property:

XLogP3:1.4
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:7
Exact Mass:280.17869263
Heavy Atom Count:20
Complexity:296

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC=CC=C1)C(CN)O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC1=CC=CC=C1)[C@H](CN)O

Technology Process of tert-butyl N-[(2S,3S)-4-amino-3-hydroxy-1-phenylbutan-2-yl]carbamate

There total 10 articles about tert-butyl N-[(2S,3S)-4-amino-3-hydroxy-1-phenylbutan-2-yl]carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 174302-74-0
(2S,3S)-N-tert-butyloxycarbonyl-2-amino-3-hydroxy-1-phenyl-4-nitrobutane

: 162541-34-6
((1S,2S)-3-Amino-1-benzyl-2-hydroxy-propyl)-carbamic acid tert-butyl ester

Guidance literature:: With hydrogen; palladium on activated charcoal; In ethanol; at 23 ℃; for 5h;
DOI:10.1002/(SICI)1521-3773(19990712)38:13/14<1931::AID-ANIE1931>3.0.CO;2-4

Reference yield:

: 1385766-21-1
tert-butyl (2S,3S)-4-azido-3-hydroxy-1-phenylbutan-2-ylcarbamate

: 162541-34-6
((1S,2S)-3-Amino-1-benzyl-2-hydroxy-propyl)-carbamic acid tert-butyl ester

Guidance literature:: With hydrogen; palladium; In isopropyl alcohol; for 2h;

Reference yield:

: 174302-72-8
(S)-3-tert-butoxycarbonylamino-1-nitro-4-phenyl-2-butanone

: 162536-42-7
(1S,2R)-(3-amino-1-benzyl-2-hydroxy-propyl)-carbamic acid tert butyl ester

: 162541-34-6
((1S,2S)-3-Amino-1-benzyl-2-hydroxy-propyl)-carbamic acid tert-butyl ester

Guidance literature:: With molecular sieve; hydrogen; platinum on activated charcoal; In isopropyl alcohol; at 35 ℃; for 17h; under 30400 Torr; Yield given. Yields of byproduct given;
DOI:10.1080/00397919808005092