Technology Process of (2-benzylprop-2-enyl) phenyl sulfone
There total 2 articles about (2-benzylprop-2-enyl) phenyl sulfone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
prop-2-ynylsulfonylbenzene;
With
Mo(CO)3(CN-t-Bu)3; tri-n-butyl-tin hydride; hydroquinone;
In
tetrahydrofuran;
for 0.283333h;
microwave irradiation;
benzyl bromide;
With
triphenylphosphine;
bis(η3-allyl-μ-chloropalladium(II));
In
tetrahydrofuran;
at 60 ℃;
for 17h;
DOI:10.1055/s-2005-868478
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: K2CO3 / methanol / 0.5 h / 0 °C
2.1: aq. H2O2; AcOH / diethyl ether / 5 h / Heating
3.1: Bu3SnH; Mo(CO)3(CN-t-Bu)3; hydroquinone / tetrahydrofuran / 0.28 h / microwave irradiation
3.2: 135 mg / PPh3 / [Pd(allyl)Cl]2 / tetrahydrofuran / 17 h / 60 °C
With
Mo(CO)3(CN-t-Bu)3; dihydrogen peroxide; tri-n-butyl-tin hydride; potassium carbonate; acetic acid; hydroquinone;
In
tetrahydrofuran; methanol; diethyl ether;
DOI:10.1055/s-2005-868478
- Guidance literature:
-
(2-benzylprop-2-enyl) phenyl sulfone;
With
n-butyllithium;
In
tetrahydrofuran;
at -40 - 20 ℃;
for 0.55h;
benzaldehyde;
In
tetrahydrofuran;
at -40 ℃;
for 0.5h;
Title compound not separated from byproducts;
DOI:10.1055/s-2005-868478
