NSC93690

Base Information

• Chemical Name: NSC93690
• CAS No.: 3166-88-9
• Molecular Formula: C10H15 N . Cl H
• Molecular Weight: 185.69374
• Hs Code.: 2921499090
• Mol file: 3166-88-9.mol

Synonyms:Benzeneethanamine,4-ethyl-, hydrochloride (9CI); Phenethylamine, p-ethyl-, hydrochloride(6CI,7CI,8CI)

Chemical Property of NSC93690

Chemical Property:

• Melting Point: 208-209℃
• PSA: 26.02000
• LogP: 3.25250

Purity/Quality:

99%min ^*data from raw suppliers

4-ETHYLPHENETHYLAMINE HYDROCHLORIDE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of NSC93690

There total 1 articles about NSC93690 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

6-chlorochromane-8-carboxylic acid chloride → 6-Chloro-N-(2-<4-ethylphenyl>-ethyl)-chromane-8-carboxylic acid amide (64353-18-0) + 4-ethyl-phenethylamine; hydrochloride (3166-88-9)

Guidance literature:

Reference yield:

4-ethyl-phenethylamine; hydrochloride (3166-88-9) + 2-methoxy-5-chlorobenzoyl chloride (29568-33-0) → 5-chloro-2-methoxy-N-<2-(p-ethylphenyl)ethyl>benzamide (64353-17-9)

Guidance literature:

With pyridine; sodium hydrogencarbonate; In toluene; Petroleum ether;

Reference yield:

ammonium hexafluorophosphate + [Ru(II)(4,4'-diethylamide-2,2'-bipyridine)2(4-carboxylicacid-4'-methyl-2,2'-bipyridine)](PF6)2 + 4-ethyl-phenethylamine; hydrochloride (3166-88-9) → Ru((C2H5)2NC(O)C5H3NNC5H3C(O)N(C2H5)2)2(CH3C5H3NNC5H3CONHCH2CH2C6H4C2H5)(2+)*2PF6(1-)=(Ru(C20H26N4O2)2(C22H23N3O))(PF6)2

Guidance literature:

With 1-hydroxybenzotriazole hydrate; 4-methylmorpholine; 4-(dimethylamino)pyridine; In N,N-dimethyl-formamide; p-CH3CH2C6H4CH2CH2NH3Cl reacted with Ru complex, benzotriazol-1-yloxy tris(dimethylamino)phosphonium hexafluorophosphate (BOP), HOBT, NMM (molar ratio 5.5:1:2:1.5:8.5) and DMAP in dry DMF at room temp.; pptd. in aq.NH4PF6: further reagents; rinsed with water and ether; purified by cation-exchange chromy. (Sephadex, NaCl soln.); elem. anal.;

DOI:10.1021/ic990819h

Downstream raw materials:

5-chloro-2-methoxy-N-<2-(p-ethylphenyl)ethyl>benzamide

Refernces