C₃₀H₃₂Cl₃NO₈

Base Information

• Chemical Name: C₃₀H₃₂Cl₃NO₈
• CAS No.: 1401413-69-1
• Molecular Formula: C₃₀H₃₂Cl₃NO₈
• Molecular Weight: 640.945
• Mol file: 1401413-69-1.mol

Synonyms:C₃₀H₃₂Cl₃NO₈

Chemical Property of C₃₀H₃₂Cl₃NO₈

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₃₀H₃₂Cl₃NO₈

There total 10 articles about C₃₀H₃₂Cl₃NO₈ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C27H31NO6 (1272755-07-3) + 2,2,2-Trichloroethyl chloroformate (17341-93-4) → C30H32Cl3NO8 (1401413-69-1)

Guidance literature:

With sodium hydrogencarbonate; In tetrahydrofuran; at 20 ℃; for 4h; Inert atmosphere;

Reference yield:

D-glucosamine hydrochloride (14131-63-6) → C30H32Cl3NO8 (1401413-69-1)

Guidance literature:

Multi-step reaction with 11 steps

1.1: sodium hydrogencarbonate / water / 0.5 h / 20 °C

1.2: 4.5 h / 20 °C

2.1: pyridine / 0 - 20 °C

3.1: boron trifluoride diethyl etherate / dichloromethane / 0 - 20 °C

4.1: zinc; acetic acid / dichloromethane; methanol / 1 h / 0 - 20 °C / Inert atmosphere

5.1: sodium methylate / dichloromethane; methanol / 2 h / 20 °C

5.2: pH ~ 7

6.1: potassium carbonate; triflic azide / zinc(II) chloride / dichloromethane; water; methanol / 20 °C

7.1: camphorsulfonic acid / toluene / 2 h / 20 °C

8.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 0 - 20 °C

9.1: trifluorormethanesulfonic acid; triethylsilane / dichloromethane / 1 h / -78 °C

10.1: sodium hydroxide; trimethylphosphane / water; tetrahydrofuran

11.1: sodium hydrogencarbonate / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

With pyridine; triethylsilane; trifluorormethanesulfonic acid; triflic azide; boron trifluoride diethyl etherate; sodium methylate; sodium hydride; sodium hydrogencarbonate; potassium carbonate; acetic acid; sodium hydroxide; zinc; trimethylphosphane; zinc(II) chloride; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; mineral oil;

Reference yield:

1,3,4,6-tetra-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranose (122210-05-3) → C30H32Cl3NO8 (1401413-69-1)

Guidance literature:

Multi-step reaction with 9 steps

1.1: boron trifluoride diethyl etherate / dichloromethane / 0 - 20 °C

2.1: zinc; acetic acid / dichloromethane; methanol / 1 h / 0 - 20 °C / Inert atmosphere

3.1: sodium methylate / dichloromethane; methanol / 2 h / 20 °C

3.2: pH ~ 7

4.1: potassium carbonate; triflic azide / zinc(II) chloride / dichloromethane; water; methanol / 20 °C

5.1: camphorsulfonic acid / toluene / 2 h / 20 °C

6.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 2 h / 0 - 20 °C

7.1: trifluorormethanesulfonic acid; triethylsilane / dichloromethane / 1 h / -78 °C

8.1: sodium hydroxide; trimethylphosphane / water; tetrahydrofuran

9.1: sodium hydrogencarbonate / tetrahydrofuran / 4 h / 20 °C / Inert atmosphere

With triethylsilane; trifluorormethanesulfonic acid; triflic azide; boron trifluoride diethyl etherate; sodium methylate; sodium hydride; sodium hydrogencarbonate; potassium carbonate; acetic acid; sodium hydroxide; zinc; trimethylphosphane; zinc(II) chloride; In tetrahydrofuran; methanol; dichloromethane; water; N,N-dimethyl-formamide; toluene; mineral oil;

upstream raw materials:

C₂₇H₃₁NO₆

2,2,2-Trichloroethyl chloroformate

D-glucosamine hydrochloride

1,3,4,6-tetra-O-acetyl-2-deoxy-2-(2,2,2-trichloroethoxycarbonylamino)-β-D-glucopyranose

Downstream raw materials:

C₄₄H₅₀Cl₃NO₁₇