methyl (R)-[(E)-1-methyl-3-phenyl-2-propenyl] carbonate

Base Information

• Chemical Name: methyl (R)-[(E)-1-methyl-3-phenyl-2-propenyl] carbonate
• CAS No.: 115340-38-0
• Molecular Formula: C₁₂H₁₄O₃
• Molecular Weight: 206.241
• Mol file: 115340-38-0.mol

Synonyms:methyl (R)-[(E)-1-methyl-3-phenyl-2-propenyl] carbonate

Chemical Property of methyl (R)-[(E)-1-methyl-3-phenyl-2-propenyl] carbonate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of methyl (R)-[(E)-1-methyl-3-phenyl-2-propenyl] carbonate

There total 1 articles about methyl (R)-[(E)-1-methyl-3-phenyl-2-propenyl] carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 49.0%

5-(1-hydroxy-1-methylethyl)-2-cyclohexenyl 3,5-dinitrobenzoate → methyl (R)-[(E)-1-methyl-3-phenyl-2-propenyl] carbonate (115340-38-0) + (E)-benzalacetone (1896-62-4)

Guidance literature:

With trans-1,2-(1S,2S)-1,2-diaminocyclohexane-N,N’-bis(2’-diphenylphosphinobenzoyl); (2-methyl-1-nitro-propyl)-benzene; potassium hexamethylsilazane; bis(η3-allyl-μ-chloropalladium(II)); In tetrahydrofuran; at 20 ℃; for 12h;

DOI:10.1021/ja057163d

Reference yield: 86.0%

methyl (R)-[(E)-1-methyl-3-phenyl-2-propenyl] carbonate (115340-38-0) + β-naphthol (135-19-3) → (R)-(+)-1-phenyl-3-(2-naphthoxy)-1-butene (223510-73-4)

Guidance literature:

With Pd₂(dpa)3; 1,4-di(diphenylphosphino)-butane; In tetrahydrofuran;

DOI:10.1021/jo982178y

Reference yield: 75.0%

methyl (R)-[(E)-1-methyl-3-phenyl-2-propenyl] carbonate (115340-38-0) + phenol (108-95-2,27073-41-2) → (R)-(+)-1-phenyl-3-phenoxy-1-butene (223510-71-2)

Guidance literature:

With tris(dibenzylideneacetone)dipalladium ⁽⁰⁾; 1,4-di(diphenylphosphino)-butane; In tetrahydrofuran;

DOI:10.1021/jo982178y

Downstream raw materials:

dimethyl <1-phenyl-2(E)-butenyl>malonate

(R)-2-(1-methyl-3-phenylallyl)malonic acid dimethyl ester

(R)-(+)-1-phenyl-3-(2-naphthoxy)-1-butene

(R)-(+)-1-phenyl-3-phenoxy-1-butene

Refernces