Quercetin 3,3',4',7-tetra(methoxymethy) ether

Base Information

• Chemical Name: Quercetin 3,3',4',7-tetra(methoxymethy) ether
• CAS No.: 143724-67-8
• Molecular Formula: C₂₃H₂₆O₁₁
• Molecular Weight: 478.453
• ChEMBL ID: CHEMBL1719176
• DSSTox Substance ID: DTXSID901122787

Synonyms:quercetin 3,3',4',7-tetra(methoxymethy) ether;MLS000697619;CHEMBL1719176;SCHEMBL15689700;DTXSID901122787;HMS2267E16;143724-67-8;SMR000470952;2-[3,4-Bis(methoxymethoxy)phenyl]-5-hydroxy-3,7-bis(methoxymethoxy)-4H-1-benzopyran-4-one

Chemical Property of Quercetin 3,3',4',7-tetra(methoxymethy) ether

Chemical Property:

• XLogP3: 3.3
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 11
• Rotatable Bond Count: 13
• Exact Mass: 478.14751164
• Heavy Atom Count: 34
• Complexity: 669

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

• Canonical SMILES: COCOC1=C(C=C(C=C1)C2=C(C(=O)C3=C(C=C(C=C3O2)OCOC)O)OCOC)OCOC

Technology Process of Quercetin 3,3',4',7-tetra(methoxymethy) ether

There total 6 articles about Quercetin 3,3',4',7-tetra(methoxymethy) ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

quercetol (117-39-5,74893-81-5) + chloromethyl methyl ether (107-30-2) → 2-(3,4-bis(methoxymethoxy)phenyl)-5-hydroxy-3,7-bis(methoxymethoxy)-4H-chromen-4-one (143724-67-8)

Guidance literature:

quercetol; With potassium carbonate; In acetone; at 20 ℃; for 0.5h;

chloromethyl methyl ether; In acetone; at 20 ℃;

DOI:10.1016/j.tetlet.2019.151138

Reference yield: 73.0%

2-(3,4-bis(methoxymethoxy)phenyl)-3,5,7-tris(methoxymethoxy)-4H-chromen-4-one → 2-(3,4-bis(methoxymethoxy)phenyl)-5-hydroxy-3,7-bis(methoxymethoxy)-4H-chromen-4-one (143724-67-8)

Guidance literature:

With hydrogenchloride; In ethanol; water; at 0 ℃; for 3h;

DOI:10.1016/j.fitote.2021.105083

Reference yield: 50.0%

quercetol (117-39-5,74893-81-5) + chloromethyl methyl ether (107-30-2) → 5-hydroxy-2-(3-hydroxy-4-(methoxymethoxy)phenyl)-3,7-bis(methoxymethoxy)-4H-chromen-4-one (1427579-73-4) + 2-(3,4-bis(methoxymethoxy)phenyl)-5-hydroxy-3,7-bis(methoxymethoxy)-4H-chromen-4-one (143724-67-8)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 - 20 ℃; for 15h; Inert atmosphere;

DOI:10.1021/jm301757v

upstream raw materials:

quercetol

chloromethyl methyl ether

rutin

Downstream raw materials:

5-O-prenyl-3,3',7,4'-tetrakis-O-methoxymethylquercetin

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 143724-67-8 2-(3,4-bis(methoxymethoxy)phenyl)-5-hydroxy-3,7-bis(methoxymethoxy)-4H-chromen-4-one

Send

Send

Metric Ton KG G Pound L ML

Send

Send