4-<2-(benzyloxy)-4-(1,1-dimethylheptyl)phenyl>-2-pentanol

Base Information

• Chemical Name: 4-<2-(benzyloxy)-4-(1,1-dimethylheptyl)phenyl>-2-pentanol
• CAS No.: 70120-01-3
• Molecular Formula: C₂₇H₄₀O₂
• Molecular Weight: 396.613
• Mol file: 70120-01-3.mol

Synonyms:4-<2-(benzyloxy)-4-(1,1-dimethylheptyl)phenyl>-2-pentanol

Chemical Property of 4-<2-(benzyloxy)-4-(1,1-dimethylheptyl)phenyl>-2-pentanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-<2-(benzyloxy)-4-(1,1-dimethylheptyl)phenyl>-2-pentanol

There total 10 articles about 4-<2-(benzyloxy)-4-(1,1-dimethylheptyl)phenyl>-2-pentanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

4-<2-(benzyloxy)-4-(1,1-dimethylheptyl)phenyl>-2-pentanone (70119-97-0) → 4-<2-(benzyloxy)-4-(1,1-dimethylheptyl)phenyl>-2-pentanol (70120-01-3)

Guidance literature:

With sodium tetrahydroborate; In tetrahydrofuran; methanol; at -40 ℃; for 1h; Yield given;

DOI:10.1021/jm00367a013

Reference yield:

2-<3-(benzyloxy)phenyl>-2-methylpropionitrile (70120-08-0) → 4-<2-(benzyloxy)-4-(1,1-dimethylheptyl)phenyl>-2-pentanol (70120-01-3)

Guidance literature:

Multi-step reaction with 8 steps

1: 1.) diisobutylaluminium hydride (DIBAL), 2.) aq. H₂SO₄ / 1.) THF, hexane, 25 deg C, 2 h, 2.) THF, hexane, 25 deg C, 2 h

2: 57 percent / DMSO, NaOH / 4 h / 15 °C

3: 78 percent / H₂ / 10percent Pd/C / ethanol / 13 h / 2585.7 Torr

4: 100 percent / Br₂ / CCl₄ / 0.25 h / 30 °C

5: 1.) KH / 1.) DMF, -18 deg C, 15 min, 2.) 25 deg C, 30 min

6: Mg / tetrahydrofuran / 20 h / Heating

7: CuI / tetrahydrofuran / 0.5 h / -3 °C

8: NaBH₄ / methanol; tetrahydrofuran / 1 h / -40 °C

With sodium hydroxide; sodium tetrahydroborate; copper(l) iodide; sulfuric acid; hydrogen; bromine; potassium hydride; diisobutylaluminium hydride; magnesium; dimethyl sulfoxide; palladium on activated charcoal; In tetrahydrofuran; methanol; tetrachloromethane; ethanol;

DOI:10.1021/jm00367a013

Reference yield:

1-(benzyloxy)-3-(1,1-dimethyl-2-heptenyl)benzene (70120-10-4) → 4-<2-(benzyloxy)-4-(1,1-dimethylheptyl)phenyl>-2-pentanol (70120-01-3)

Guidance literature:

Multi-step reaction with 6 steps

1: 78 percent / H₂ / 10percent Pd/C / ethanol / 13 h / 2585.7 Torr

2: 100 percent / Br₂ / CCl₄ / 0.25 h / 30 °C

3: 1.) KH / 1.) DMF, -18 deg C, 15 min, 2.) 25 deg C, 30 min

4: Mg / tetrahydrofuran / 20 h / Heating

5: CuI / tetrahydrofuran / 0.5 h / -3 °C

6: NaBH₄ / methanol; tetrahydrofuran / 1 h / -40 °C

With sodium tetrahydroborate; copper(l) iodide; hydrogen; bromine; potassium hydride; magnesium; palladium on activated charcoal; In tetrahydrofuran; methanol; tetrachloromethane; ethanol;

DOI:10.1021/jm00367a013

upstream raw materials:

4-<2-(benzyloxy)-4-(1,1-dimethylheptyl)phenyl>-2-pentanone

1-bromo-2-benzyloxy-4-(1,1-dimethylheptyl)benzene

2-(3-hydroxyphenyl)-2-methyloctane

2-(4-bromo-3-hydroxyphenyl)-2-methyloctane

Downstream raw materials:

4-<4-(1,1-dimethylheptyl)-2-hydroxyphenyl>-2-pentanol