9-(tert-butyl-dimethyl-silanyloxy)-4-methyl-naphtho[2,3-b]furan-3-carboxylic acid benzyl ester

Base Information

• Chemical Name: 9-(tert-butyl-dimethyl-silanyloxy)-4-methyl-naphtho[2,3-b]furan-3-carboxylic acid benzyl ester
• CAS No.: 950906-66-8
• Molecular Formula: C₂₇H₃₀O₄Si
• Molecular Weight: 446.618

Synonyms:9-(tert-butyl-dimethyl-silanyloxy)-4-methyl-naphtho[2,3-b]furan-3-carboxylic acid benzyl ester

Chemical Property of 9-(tert-butyl-dimethyl-silanyloxy)-4-methyl-naphtho[2,3-b]furan-3-carboxylic acid benzyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 9-(tert-butyl-dimethyl-silanyloxy)-4-methyl-naphtho[2,3-b]furan-3-carboxylic acid benzyl ester

There total 1 articles about 9-(tert-butyl-dimethyl-silanyloxy)-4-methyl-naphtho[2,3-b]furan-3-carboxylic acid benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 76.0%

4-[2-(4-methyl-oxazole-5-carbonyl)-phenyl]-pent-2-ynoic acid benzyl ester + tert-butyldimethylsilyl chloride (18162-48-6) → 9-(tert-butyl-dimethyl-silanyloxy)-4-methyl-naphtho[2,3-b]furan-3-carboxylic acid benzyl ester (950906-66-8)

Guidance literature:

4-[2-(4-methyl-oxazole-5-carbonyl)-phenyl]-pent-2-ynoic acid benzyl ester; In o-xylene; for 5h; Heating;

tert-butyldimethylsilyl chloride; With 1H-imidazole; dmap; In o-xylene; at 20 ℃; for 18h; Further stages.;

DOI:10.1021/ol071158s

Reference yield: 67.0%

9-(tert-butyl-dimethyl-silanyloxy)-4-methyl-naphtho[2,3-b]furan-3-carboxylic acid benzyl ester (950906-66-8) + formaldehyd (50-00-0,30525-89-4,61233-19-0) → benzyl 4,9-dihydro-4-(hydroxymethyl)-4-methyl-9-oxonaphtho[2,3-b]furan-3-carboxylate (950906-68-0)

Guidance literature:

With titanium tetrachloride; In dichloromethane; at 20 ℃; for 0.5h;

DOI:10.1021/ol071158s

Reference yield:

9-(tert-butyl-dimethyl-silanyloxy)-4-methyl-naphtho[2,3-b]furan-3-carboxylic acid benzyl ester (950906-66-8) + glyoxylic acid ethyl ester (924-44-7) → C25H22O7

Guidance literature:

With titanium tetrachloride; In dichloromethane; at 20 ℃; for 0.25h;

DOI:10.1021/ol071158s

upstream raw materials:

tert-butyldimethylsilyl chloride

Downstream raw materials:

benzyl 4,9-dihydro-4-(hydroxymethyl)-4-methyl-9-oxonaphtho[2,3-b]furan-3-carboxylate

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 950906-66-8 9-(tert-butyl-dimethyl-silanyloxy)-4-methyl-naphtho[2,3-b]furan-3-carboxylic acid benzyl ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send