3β-hydroxy-pregn-5-en-17β-yl-3'-(p-methoxy)-phenylprop-2'-en-1'-one

Base Information

• Chemical Name: 3β-hydroxy-pregn-5-en-17β-yl-3'-(p-methoxy)-phenylprop-2'-en-1'-one
• CAS No.: 1034000-86-6
• Molecular Formula: C₂₉H₃₈O₃
• Molecular Weight: 434.619
• Mol file: 1034000-86-6.mol

Synonyms:3β-hydroxy-pregn-5-en-17β-yl-3'-(p-methoxy)-phenylprop-2'-en-1'-one

Chemical Property of 3β-hydroxy-pregn-5-en-17β-yl-3'-(p-methoxy)-phenylprop-2'-en-1'-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of 3β-hydroxy-pregn-5-en-17β-yl-3'-(p-methoxy)-phenylprop-2'-en-1'-one

There total 1 articles about 3β-hydroxy-pregn-5-en-17β-yl-3'-(p-methoxy)-phenylprop-2'-en-1'-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.16%

Pregnenolone (145-13-1) + 4-methoxy-benzaldehyde (123-11-5) → 3β-hydroxy-pregn-5-en-17β-yl-3'-(p-methoxy)-phenylprop-2'-en-1'-one (1034000-86-6)

Guidance literature:

With sodium hydroxide; In ethanol; water; at 20 ℃; for 48h;

DOI:10.1016/j.steroids.2021.108830

Reference yield: 84.0%

3β-hydroxy-pregn-5-en-17β-yl-3'-(p-methoxy)-phenylprop-2'-en-1'-one (1034000-86-6) + acetic acid (64-19-7,77671-22-8) → 1-(4,5-dihydro-3-((10R,13S)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3-hydroxy-10,13-dimethyl-1H-cyclopenta[a]phenanthren-17-yl)-5-(4-methoxyphenyl)pyrazol-1-yl)ethanone (1251915-86-2)

Guidance literature:

With hydrazine hydrate; Reflux;

DOI:10.1016/j.steroids.2010.02.014

Reference yield: 80.88%

3β-hydroxy-pregn-5-en-17β-yl-3'-(p-methoxy)-phenylprop-2'-en-1'-one (1034000-86-6) + thiosemicarbazide (79-19-6) → C30H41N3O2S

Guidance literature:

With sodium hydroxide; In ethanol; for 12h;

DOI:10.1016/j.steroids.2019.03.012

upstream raw materials:

Pregnenolone

4-methoxy-benzaldehyde

Downstream raw materials:

1-(4,5-dihydro-3-((10R,13S)-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-3-hydroxy-10,13-dimethyl-1H-cyclopenta[a]phenanthren-17-yl)-5-(4-methoxyphenyl)pyrazol-1-yl)ethanone