tert-butyl N-{2-[4-(aMinoMethyl)benzaMido]phenyl}carbaMate

Base Information

Chemical Name:tert-butyl N-{2-[4-(aMinoMethyl)benzaMido]phenyl}carbaMate
CAS No.:209784-85-0
Molecular Formula:C₁₉H₂₃N₃O₃
Molecular Weight:341.41
Hs Code.:
Mol file:209784-85-0.mol

Synonyms:[2-(4-aminomethylbenzoylamino)phenyl]carbamic acid tert-butyl ester

Suppliers and Price of tert-butyl N-{2-[4-(aMinoMethyl)benzaMido]phenyl}carbaMate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
[2-[[4-(Aminomethyl)benzoyl]amino]phenyl]-carbamicAcidtert-ButylEster
100mg
$ 165.00

Total 1 raw suppliers

Chemical Property of tert-butyl N-{2-[4-(aMinoMethyl)benzaMido]phenyl}carbaMate

Chemical Property:

Purity/Quality:: [2-[[4-(Aminomethyl)benzoyl]amino]phenyl]-carbamicAcidtert-ButylEster ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses [2-[[4-(Aminomethyl)benzoyl]amino]phenyl]-carbamic Acid tert-Butyl Ester is a reactant for the preparation of benzamide derivatives for enzyme inhibitors and anticancer agents

Technology Process of tert-butyl N-{2-[4-(aMinoMethyl)benzaMido]phenyl}carbaMate

There total 10 articles about tert-butyl N-{2-[4-(aMinoMethyl)benzaMido]phenyl}carbaMate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 209784-84-9
tert-butyl-(2-(4-((2,2,2-trifluoroacetamido)methyl)benzamido)phenyl)carbamate

: 209784-85-0
[2-(4-aminomethylbenzoylamino)phenyl]carbamic acid tert-butyl ester

Guidance literature:: With potassium carbonate; In methanol; water; at 25 ℃; for 10h;
DOI:10.2174/1573406411666150714111045

Reference yield:

: 146651-75-4
tert–butyl (2–aminophenyl)carbamate

: 209784-85-0
[2-(4-aminomethylbenzoylamino)phenyl]carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 3 h / 20 °C

2: ammonia; potassium iodide; potassium carbonate / acetonitrile / 12 h / Reflux

With ammonia; potassium carbonate; triethylamine; potassium iodide; In dichloromethane; acetonitrile;
DOI:10.1021/cn500021p

Reference yield:

: 876-08-4
p-(chloromethyl)benzoyl chloride

: 209784-85-0
[2-(4-aminomethylbenzoylamino)phenyl]carbamic acid tert-butyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 3 h / 20 °C

2: ammonia; potassium iodide; potassium carbonate / acetonitrile / 12 h / Reflux

With ammonia; potassium carbonate; triethylamine; potassium iodide; In dichloromethane; acetonitrile;
DOI:10.1021/cn500021p