Phosphonic acid, (carbamoylmethyl)-, diethyl ester

Base Information

• Chemical Name: Phosphonic acid, (carbamoylmethyl)-, diethyl ester
• CAS No.: 5464-68-6
• Molecular Formula: C6H14NO4P
• Molecular Weight: 195.155
• Hs Code.: 2931900090
• Mol file: 5464-68-6.mol

Synonyms:diethyl ester of 2-amino-2-oxoethylphosphonic acid;Diethyl carbamoylmethylphosphonate;Diethylphosphonoacetamide;diethyl aminocarbonylmethylphosphonate;2-amino-2-oxoethylphosphonic acid diethyl ester;

Chemical Property of Phosphonic acid, (carbamoylmethyl)-, diethyl ester

Chemical Property:

• Vapor Pressure: 9.52E-05mmHg at 25°C
• Melting Point: 78-80 °C
• Boiling Point: 338.9ºC at 760 mmHg
• PKA: 15.46±0.40(Predicted)
• Flash Point: 158.8ºC
• PSA: 88.43000
• Density: 1.18g/cm3
• LogP: 1.43810
• Storage Temp.: Sealed in dry,Room Temperature

Purity/Quality:

99% ^*data from raw suppliers

Diethyl(2-Amino-2-oxoethyl)phosphonate ^*data from reagent suppliers

Safty Information:

• Pictogram(s): 1777584
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Phosphonic acid, (carbamoylmethyl)-, diethyl ester

There total 5 articles about Phosphonic acid, (carbamoylmethyl)-, diethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

bromo-acetic acid amide (683-57-8) + triethyl phosphite (122-52-1) → diethyl carbamoylmethylphosphonate (5464-68-6)

Guidance literature:

for 0.0166667h; microwave irradiation;

DOI:10.1080/10426500008043680

Reference yield: 72.0%

Chloroacetamide (79-07-2) + triethyl phosphite (122-52-1) → diethyl carbamoylmethylphosphonate (5464-68-6)

Guidance literature:

at 150 ℃; for 8h; Inert atmosphere;

DOI:10.1021/jo9018705

Reference yield:

diethoxyphosphoryl-acetic acid ethyl ester (867-13-0) → diethyl carbamoylmethylphosphonate (5464-68-6)

Guidance literature:

With ammonia; at 25 ℃;

DOI:10.1111/j.1748-5827.2000.tb03158.x

upstream raw materials:

diethoxyphosphoryl-acetic acid ethyl ester

Chloroacetamide

triethyl phosphite

bromo-acetic acid amide

Downstream raw materials:

C-Cyclohexyliden-acetamid

[(E)-1-Carbamoyl-2-(4-nitro-phenyl)-vinyl]-phosphonic acid diethyl ester

((E)-1-Carbamoyl-2-phenyl-vinyl)-phosphonic acid diethyl ester

Hex-2-ensaeure-amid