4-(5,6,7,8-Tetramethoxy-4-oxo-4H-chromen-2-yl)phenyl acetate

Base Information

Chemical Name:4-(5,6,7,8-Tetramethoxy-4-oxo-4H-chromen-2-yl)phenyl acetate
CAS No.:6959-55-3
Molecular Formula:C21H20 O8
Molecular Weight:400.3787
Hs Code.:
NSC Number:66067
DSSTox Substance ID:DTXSID80219855
Nikkaji Number:J2.791.373C
Wikidata:Q27148567
ChEMBL ID:CHEMBL490975

Synonyms:6959-55-3;4-(5,6,7,8-Tetramethoxy-4-oxo-4H-chromen-2-yl)phenyl acetate;NSC 66067;CHEBI:79487;NSC66067;NSC-66067;2-[4-(Acetyloxy)phenyl]-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one;NCIOpen2_008152;CHEMBL490975;DTXSID80219855;Q27148567;[4-(5,6,7,8-tetramethoxy-4-oxo-chromen-2-yl)phenyl] acetate;2-(4-Acetoxyphenyl)-5,6,7,8-tetramethoxy-4H-1-benzopyran-4-one;4-(5,6,7,8-tetramethoxy-4-oxo-4H-1-benzopyran-2-yl)phenyl acetate

Suppliers and Price of 4-(5,6,7,8-Tetramethoxy-4-oxo-4H-chromen-2-yl)phenyl acetate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 4-(5,6,7,8-Tetramethoxy-4-oxo-4H-chromen-2-yl)phenyl acetate

Chemical Property:

Vapor Pressure:6.9E-14mmHg at 25°C
Boiling Point:589.8°C at 760 mmHg
Flash Point:257.7°C
Density:1.279g/cm³
XLogP3:2.8
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:8
Rotatable Bond Count:7
Exact Mass:400.11581759
Heavy Atom Count:29
Complexity:624

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)OC1=CC=C(C=C1)C2=CC(=O)C3=C(O2)C(=C(C(=C3OC)OC)OC)OC

Technology Process of 4-(5,6,7,8-Tetramethoxy-4-oxo-4H-chromen-2-yl)phenyl acetate

There total 7 articles about 4-(5,6,7,8-Tetramethoxy-4-oxo-4H-chromen-2-yl)phenyl acetate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 53.0%

: 36950-98-8
4'-hydroxy-5,6,7,8-tetramethoxy flavone

: 108-24-7
acetic anhydride

: 6959-55-3
Acetic acid 4-(5,6,7,8-tetramethoxy-4-oxo-4H-chromen-2-yl)-phenyl ester

Guidance literature:: With pyridine; at 20 ℃; for 3h;
DOI:10.1021/np070084q

Reference yield:

: 40110-96-1
4'-benzyloxy-5,6,7,8-tetramethoxyflavone

: 6959-55-3
Acetic acid 4-(5,6,7,8-tetramethoxy-4-oxo-4H-chromen-2-yl)-phenyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 95 percent / H₂ / Pd-C / dimethylformamide / 20 °C

2: 53 percent / pyridine / 3 h / 20 °C

With pyridine; hydrogen; palladium on activated charcoal; In N,N-dimethyl-formamide;
DOI:10.1021/np070084q

Reference yield:

: 3162-28-5
2-hydroxy-3,4,5,6-tetramethoxyacetophenone

: 6959-55-3
Acetic acid 4-(5,6,7,8-tetramethoxy-4-oxo-4H-chromen-2-yl)-phenyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 51 percent / NaH / tetrahydrofuran / 4 h / Heating

2: 54 percent / I₂; pyridine / 9 h / 120 °C

3: 95 percent / H₂ / Pd-C / dimethylformamide / 20 °C

4: 53 percent / pyridine / 3 h / 20 °C

With pyridine; hydrogen; iodine; sodium hydride; palladium on activated charcoal; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/np070084q