(E)-2-(5-nitro-2-styryl-1H-imidazol-1-yl)ethyl isoquinoline-1-carboxylate

Base Information

Chemical Name:(E)-2-(5-nitro-2-styryl-1H-imidazol-1-yl)ethyl isoquinoline-1-carboxylate
CAS No.:1627199-08-9
Molecular Formula:C₂₃H₁₈N₄O₄
Molecular Weight:414.42
Hs Code.:

Synonyms:(E)-2-(5-nitro-2-styryl-1H-imidazol-1-yl)ethyl isoquinoline-1-carboxylate

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Chemical Property of (E)-2-(5-nitro-2-styryl-1H-imidazol-1-yl)ethyl isoquinoline-1-carboxylate

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Technology Process of (E)-2-(5-nitro-2-styryl-1H-imidazol-1-yl)ethyl isoquinoline-1-carboxylate

There total 7 articles about (E)-2-(5-nitro-2-styryl-1H-imidazol-1-yl)ethyl isoquinoline-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.3%

: 1627199-09-0
C₁₆H₁₄N₄O₄

: 100-52-7
benzaldehyde

: 1627199-08-9
(E)-2-(5-nitro-2-styryl-1H-imidazol-1-yl)ethyl isoquinoline-1-carboxylate

Guidance literature:: With sodium hydroxide; In methanol; water; dimethyl sulfoxide; at 20 ℃;
DOI:10.1039/c4ra01936a

Reference yield:

: 486-73-7
1-isoquinolinecarboxylic acid

: 1569313-27-4
C₂₀H₁₉N₃O₅S

: 1627199-08-9
(E)-2-(5-nitro-2-styryl-1H-imidazol-1-yl)ethyl isoquinoline-1-carboxylate

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 20 ℃; Reflux;
DOI:10.1039/c4ra01936a

Reference yield:

: 38318-92-2
2-{5-nitro-2-[(E)-2-phenylethenyl]-1H-imidazol-1-yl}ethanol

: 1627199-08-9
(E)-2-(5-nitro-2-styryl-1H-imidazol-1-yl)ethyl isoquinoline-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / dichloromethane / 5 h / 20 °C

2: potassium carbonate / N,N-dimethyl-formamide / 20 °C / Reflux

With potassium carbonate; triethylamine; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c4ra01936a