C₁₉H₁₉NO₂

Base Information

• Chemical Name: C₁₉H₁₉NO₂
• CAS No.: 1320362-87-5
• Molecular Formula: C₁₉H₁₉NO₂
• Molecular Weight: 293.365
• Mol file: 1320362-87-5.mol

Synonyms:C₁₉H₁₉NO₂

Chemical Property of C₁₉H₁₉NO₂

Chemical Property:

Purity/Quality:

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Technology Process of C₁₉H₁₉NO₂

There total 1 articles about C₁₉H₁₉NO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-chloro-6-methoxyquinolin-3-carboxaldehyde (73568-29-3) + 2-cyclohexylacetylene (931-48-6) → C19H19NO2 (1320362-87-5)

Guidance literature:

With trans-bis(triphenylphosphine)palladium dichloride; triethylamine; at 60 ℃;

DOI:10.1021/co200100z

Reference yield: 58.0%

C19H19NO2 (1320362-87-5) → 2-(cyclohexylethynyl)-6-methoxyquinolin-3-amine

Guidance literature:

With caesium carbonate; N-fluorobis(benzenesulfon)imide; In N,N-dimethyl acetamide; at 80 ℃; for 24h;

DOI:10.1002/chem.201903495

Reference yield:

methanol (67-56-1) + C19H19NO2 (1320362-87-5) → C20H22INO3 (1320362-81-9)

Guidance literature:

With iodine; potassium carbonate; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1021/co200100z

upstream raw materials:

2-chloro-6-methoxyquinolin-3-carboxaldehyde

2-cyclohexylacetylene

Downstream raw materials:

C₂₀H₂₂INO₃