(((3-methylphenyl)amino)carbonyl)ferrocene

Base Information

• Chemical Name: (((3-methylphenyl)amino)carbonyl)ferrocene
• CAS No.: 220113-16-6
• Molecular Formula: C₁₈H₁₇FeNO
• Molecular Weight: 319.186
• Mol file: 220113-16-6.mol

Synonyms:(((3-methylphenyl)amino)carbonyl)ferrocene

Chemical Property of (((3-methylphenyl)amino)carbonyl)ferrocene

Chemical Property:

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Technology Process of (((3-methylphenyl)amino)carbonyl)ferrocene

There total 1 articles about (((3-methylphenyl)amino)carbonyl)ferrocene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

ferrocenoyl chloride (1293-79-4) + 1-amino-3-methylbenzene (108-44-1) → (((3-methylphenyl)amino)carbonyl)ferrocene (220113-16-6)

Guidance literature:

With NEt₃; In dichloromethane; (N2); addn. of the complex in CH2Cl2 to the pyridine derivative and NEt3 in CH2Cl2 at 0°C over a period of 30 min, warming to room temp., stirring (24 h); filtration, addn. of satd. NaHCO3, extraction (CH2Cl2), drying (MgSO4),filtration, solvent removal (reduced pressure), column chromy. (neutralalumina, CH2Cl2/MeOH 99:1), recrystn. (CH2Cl2/Et2O); elem. anal.;

DOI:10.1039/a807453d

Reference yield: 68.0%

(((3-methylphenyl)amino)carbonyl)ferrocene (220113-16-6) + diphenyl acetylene (501-65-5) → 4-(3-methylphenyl)-5,6-diphenylferrocene[1,2-c]pyridine-3(4H)-one (1603897-51-3)

Guidance literature:

With tetrabutylammomium bromide; palladium diacetate; copper(II) acetate monohydrate; sodium hydrogencarbonate; In toluene; at 90 ℃; for 12h; Schlenk technique;

DOI:10.1021/om5002606

upstream raw materials:

ferrocenoyl chloride

1-amino-3-methylbenzene

Downstream raw materials:

4-(3-methylphenyl)-5,6-diphenylferrocene[1,2-c]pyridine-3(4H)-one

Refernces