(S)-ethyl 2-(((S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl)amino)-4-fluoro-4-methylpentanoate

Base Information

Chemical Name:(S)-ethyl 2-(((S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl)amino)-4-fluoro-4-methylpentanoate
CAS No.:1112233-63-2
Molecular Formula:C₁₆H₂₀BrF₄NO₂
Molecular Weight:414.238
Hs Code.:

Synonyms:(S)-ethyl 2-(((S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl)amino)-4-fluoro-4-methylpentanoate

Suppliers and Price of (S)-ethyl 2-(((S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl)amino)-4-fluoro-4-methylpentanoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (S)-ethyl 2-(((S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl)amino)-4-fluoro-4-methylpentanoate

Chemical Property:

Purity/Quality:: ≥98% ^*data from raw suppliers

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Technology Process of (S)-ethyl 2-(((S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl)amino)-4-fluoro-4-methylpentanoate

There total 1 articles about (S)-ethyl 2-(((S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl)amino)-4-fluoro-4-methylpentanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1112233-60-9
(1R)-1-(4-bromophenyl)-2,2,2-trifluoroethyl trifluoromethanesulfonate

: 156047-39-1,885498-60-2
ethyl (2S)-2-amino-4-fluoro-4-methylpentanoate

: 1112233-63-2
(S)-ethyl 2-(((S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl)amino)-4-fluoro-4-methylpentanoate

: ethyl N-[(1R)-1-(4-bromophenyl)-2,2,2-trifluoroethyl]-4-fluoro-L-leucinate

Guidance literature:: With potassium carbonate; In cyclohexane; at 65 - 70 ℃; for 24h; optical yield given as %de; Large scale reaction;
DOI:10.1021/jo8020314

Reference yield:

: 1112233-63-2
(S)-ethyl 2-(((S)-1-(4-bromophenyl)-2,2,2-trifluoroethyl)amino)-4-fluoro-4-methylpentanoate

: 73183-34-3
bis(pinacol)diborane

: 1136103-26-8
ethyl 4-fluoro-N-{(1S)-2,2,2-trifluoro-1-[4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl]ethyl}-L-leucinate

Guidance literature:: With potassium acetate; (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride; In N,N-dimethyl-formamide; at 20 - 70 ℃;