(E)-methyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-styrylbenzoate

Base Information

• Chemical Name: (E)-methyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-styrylbenzoate
• CAS No.: 1363155-62-7
• Molecular Formula: C₂₂H₂₄O₄
• Molecular Weight: 352.43
• Mol file: 1363155-62-7.mol

Synonyms:(E)-methyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-styrylbenzoate

Chemical Property of (E)-methyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-styrylbenzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E)-methyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-styrylbenzoate

There total 11 articles about (E)-methyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-styrylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

→ (E)-methyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-styrylbenzoate (1363155-62-7)

Guidance literature:

With palladium diacetate; triphenylphosphine; In N,N-dimethyl-formamide; at 100 ℃; for 12h;

Reference yield: 75.0%

methyl 6-formyl-2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)benzoate + benzaldehyde (100-52-7) → (E)-methyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-styrylbenzoate (1363155-62-7)

Guidance literature:

With titanium tetrachloride; zinc; In tetrahydrofuran; Reflux;

DOI:10.1016/j.cclet.2019.04.043

Reference yield: 61.0%

(E)-2-hydroxy-4-methoxy-6-[styryl]benzoic acid methyl ester + prenyl bromide (870-63-3) → (E)-methyl 2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-styrylbenzoate (1363155-62-7)

Guidance literature:

(E)-2-hydroxy-4-methoxy-6-[styryl]benzoic acid methyl ester; With sodium; In diethyl ether; at 20 ℃; for 4h;

prenyl bromide; In diethyl ether; for 4h; Reflux;

upstream raw materials:

(E)-2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-styrylbenzoic acid

methyl iodide

methyl 2,4-dimethoxy-6-methylbenzoate

2-bromomethyl-4,6-dimethoxy-benzoic acid methyl ester

Downstream raw materials:

(E)-2-hydroxy-4-methoxy-3-(3-methylbut-2-en-1-yl)-6-styrylbenzoic acid

(E)-3-methoxy-2-(3-methylbut-2-en-1-yl)-5-styrylphenol