3-(2-Aminophenyl)-2-phenylacrylic acid

Base Information

• Chemical Name: 3-(2-Aminophenyl)-2-phenylacrylic acid
• CAS No.: 5328-96-1
• Molecular Formula: C15H13NO2
• Molecular Weight: 306.337
• NSC Number: 1850
• Mol file: 5328-96-1.mol

Synonyms:NSC1850;3-(2-AMINOPHENYL)-2-PHENYLACRYLIC ACID;NSC-1850;3-(2-aminophenyl)-2-phenylprop-2-enoic acid

Chemical Property of 3-(2-Aminophenyl)-2-phenylacrylic acid

Chemical Property:

• Density: 1.318g/cm³
• XLogP3: 2.8
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 3
• Exact Mass: 239.094628657
• Heavy Atom Count: 18
• Complexity: 319

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=CC2=CC=CC=C2N)C(=O)O
• Isomeric SMILES: C1=CC=C(C=C1)/C(=C/C2=CC=CC=C2N)/C(=O)O

Technology Process of 3-(2-Aminophenyl)-2-phenylacrylic acid

There total 3 articles about 3-(2-Aminophenyl)-2-phenylacrylic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

(Z)-3-(2-nitrophenyl)-2-phenylprop-2-enoic acid (19393-14-7) + ammonia (7664-41-7) + iron(II) sulfate → α-Phenyl-o-aminozimtsaeure (5328-96-1,71910-54-8)

Guidance literature:

Reference yield:

(E)-2-phenyl-3-(2-nitrophenyl)propenoic acid (19319-35-8) + ammonia (7664-41-7) + iron(II) sulfate → α-Phenyl-o-aminozimtsaeure (5328-96-1,71910-54-8)

Guidance literature:

Reference yield:

→ α-Phenyl-o-aminozimtsaeure (5328-96-1,71910-54-8)

Guidance literature:

o-Iodanilin, α-Phenylacrylsaeure, Pd-acetat;

DOI:10.1021/ja00512a028

upstream raw materials:

(Z)-3-(2-nitrophenyl)-2-phenylprop-2-enoic acid

ammonia

(E)-2-phenyl-3-(2-nitrophenyl)propenoic acid

Downstream raw materials:

(Z)-2,3-diphenylprop-2-enoic acid