4-(4-methoxyphenyl)-2-(toluene-4-sulfonyl)-2,3-dihydro-1H-benzo[f]isoindole

Base Information

• Chemical Name: 4-(4-methoxyphenyl)-2-(toluene-4-sulfonyl)-2,3-dihydro-1H-benzo[f]isoindole
• CAS No.: 1599470-86-6
• Molecular Formula: C₂₆H₂₃NO₃S
• Molecular Weight: 429.54
• Mol file: 1599470-86-6.mol

Synonyms:4-(4-methoxyphenyl)-2-(toluene-4-sulfonyl)-2,3-dihydro-1H-benzo[f]isoindole

Chemical Property of 4-(4-methoxyphenyl)-2-(toluene-4-sulfonyl)-2,3-dihydro-1H-benzo[f]isoindole

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-(4-methoxyphenyl)-2-(toluene-4-sulfonyl)-2,3-dihydro-1H-benzo[f]isoindole

There total 3 articles about 4-(4-methoxyphenyl)-2-(toluene-4-sulfonyl)-2,3-dihydro-1H-benzo[f]isoindole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

N-(3-(4-methoxyphenyl)prop-2-yn-1-yl)-4-methyl-N-(3-phenylprop-2-yn-1-yl)benzenesulfonamide (1352213-67-2) → 6-methoxy-4-phenyl-2-(toluene-4-sulfonyl)-2,3-dihydro-1H-benzo[f]isoindole (1599470-85-5) + 4-(4-methoxyphenyl)-2-(toluene-4-sulfonyl)-2,3-dihydro-1H-benzo[f]isoindole (1599470-86-6)

Guidance literature:

With aluminum oxide; In dichloromethane; at 130 ℃; Overall yield = 85 %; Green chemistry;

DOI:10.1016/j.tetlet.2014.05.033

Reference yield:

C26H25NO3S → 4-(4-methoxyphenyl)-2-(toluene-4-sulfonyl)-2,3-dihydro-1H-benzo[f]isoindole (1599470-86-6) + C26H25NO3S

Guidance literature:

With iron(III) chloride; iron(II) acetylacetonate; In chlorobenzene; at 150 ℃; for 5h; Overall yield = 57 %; Overall yield = 25 mg; Microwave irradiation; Sealed tube;

DOI:10.1021/acs.joc.7b02672

Reference yield:

→ 4-(4-methoxyphenyl)-2-(toluene-4-sulfonyl)-2,3-dihydro-1H-benzo[f]isoindole (1599470-86-6) + C26H25NO3S

Guidance literature:

With iron(III) chloride; iron(II) diacetylacetonate; In chlorobenzene; at 150 ℃; for 5h; Overall yield = 57 percent; Microwave irradiation; Sealed tube;

upstream raw materials:

N-(3-(4-methoxyphenyl)prop-2-yn-1-yl)-4-methyl-N-(3-phenylprop-2-yn-1-yl)benzenesulfonamide