(E,R)-acetic acid-1,4-dimethyl-3-phenyl-2-pentenyl ester

Base Information

• Chemical Name: (E,R)-acetic acid-1,4-dimethyl-3-phenyl-2-pentenyl ester
• CAS No.: 858932-56-6
• Molecular Formula: C₁₅H₂₀O₂
• Molecular Weight: 232.323
• Mol file: 858932-56-6.mol

Synonyms:(E,R)-acetic acid-1,4-dimethyl-3-phenyl-2-pentenyl ester

Chemical Property of (E,R)-acetic acid-1,4-dimethyl-3-phenyl-2-pentenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (E,R)-acetic acid-1,4-dimethyl-3-phenyl-2-pentenyl ester

There total 5 articles about (E,R)-acetic acid-1,4-dimethyl-3-phenyl-2-pentenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

vinyl acetate (108-05-4,9003-20-7) + (E)-5-methyl-4-phenyl-3-hexen-2-ol (858932-54-4) → (E,S)-5-methyl-4-phenyl-3-hexen-2-ol (858932-57-7) + (E,R)-5-methyl-4-phenyl-3-hexen-2-ol (858932-58-8) + (E,R)-acetic acid-1,4-dimethyl-3-phenyl-2-pentenyl ester (858932-56-6)

Guidance literature:

With Burkholderia cepacia lipase; In diethyl ether;

DOI:10.1055/s-2005-861856

Reference yield:

trans-3-Phenyl-4-methyl-2-penten-1-al (92421-14-2) → (E,R)-acetic acid-1,4-dimethyl-3-phenyl-2-pentenyl ester (858932-56-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 27.6 g / diethyl ether / 2 h

2: 42 percent / Burkholderia cepacia lipase / diethyl ether; various solvent(s)

With Burkholderia cepacia lipase; In diethyl ether;

DOI:10.1055/s-2005-861856

Reference yield:

(E)-ethyl 4-methyl-3-phenylpent-2-enoate (62751-30-8,126275-04-5,62713-10-4) → (E,R)-acetic acid-1,4-dimethyl-3-phenyl-2-pentenyl ester (858932-56-6)

Guidance literature:

Multi-step reaction with 4 steps

1: Red-Al / tetrahydrofuran; toluene / 20 °C

2: MnO₂ / CH₂Cl₂ / 24 h / 20 °C

3: 27.6 g / diethyl ether / 2 h

4: 42 percent / Burkholderia cepacia lipase / diethyl ether; various solvent(s)

With Burkholderia cepacia lipase; manganese(IV) oxide; sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; diethyl ether; dichloromethane; toluene;

DOI:10.1055/s-2005-861856

upstream raw materials:

vinyl acetate

(E)-5-methyl-4-phenyl-3-hexen-2-ol

trans-3-Phenyl-4-methyl-2-penten-1-al

(E)-ethyl 4-methyl-3-phenylpent-2-enoate

Downstream raw materials:

(2R,4R)-4-hydroxy-2-isopropyl-2-phenylpentanenitrile

(2R,4S)-4-hydroxy-2-isopropyl-2-phenylpentanenitrile

(E)-(S)-3-Isopropyl-3-phenyl-hex-4-enoic acid ethyl ester

Acetic acid (E)-(S)-3-isopropyl-1-methyl-3-phenyl-hex-4-enyl ester