2-(2-fluorobiphenyl-4-yl)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazole

Base Information

Chemical Name:2-(2-fluorobiphenyl-4-yl)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazole
CAS No.:1394893-06-1
Molecular Formula:C₂₂H₁₃F₂N₃S
Molecular Weight:389.428
Hs Code.:

Synonyms:2-(2-fluorobiphenyl-4-yl)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazole

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(2-fluorobiphenyl-4-yl)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazole

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Technology Process of 2-(2-fluorobiphenyl-4-yl)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazole

There total 2 articles about 2-(2-fluorobiphenyl-4-yl)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

: 1394893-03-8
C₁₄H₁₀FN₃S

: 403-29-2
2-bromo-4'-fluoroacetophenone

: 1394893-06-1
2-(2-fluorobiphenyl-4-yl)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazole

Guidance literature:: With N,N-dimethyl-formamide; In ethanol; Reflux;
DOI:10.1016/j.ejmech.2012.08.012

Reference yield:

: 137045-30-8
2-fluoro-4-biphenylacetic acid

: 1394893-06-1
2-(2-fluorobiphenyl-4-yl)-6-(4-fluorophenyl)imidazo[2,1-b][1,3,4]thiadiazole

Guidance literature:: Multi-step reaction with 2 steps

1: trichlorophosphate

2: N,N-dimethyl-formamide / ethanol / Reflux

With N,N-dimethyl-formamide; trichlorophosphate; In ethanol;
DOI:10.1016/j.ejmech.2012.08.012