2,4-Dimethoxy-6-[1-phenylsulfanyl-5-(toluene-4-sulfonyloxy)-pentyl]-benzoic acid 5-cyano-5-(1-ethoxy-ethoxy)-1-methyl-pentyl ester

Base Information

• Chemical Name: 2,4-Dimethoxy-6-[1-phenylsulfanyl-5-(toluene-4-sulfonyloxy)-pentyl]-benzoic acid 5-cyano-5-(1-ethoxy-ethoxy)-1-methyl-pentyl ester
• CAS No.: 84597-65-9
• Molecular Formula: C₃₈H₄₉NO₉S₂
• Molecular Weight: 727.94
• Mol file: 84597-65-9.mol

Synonyms:2,4-Dimethoxy-6-[1-phenylsulfanyl-5-(toluene-4-sulfonyloxy)-pentyl]-benzoic acid 5-cyano-5-(1-ethoxy-ethoxy)-1-methyl-pentyl ester

Chemical Property of 2,4-Dimethoxy-6-[1-phenylsulfanyl-5-(toluene-4-sulfonyloxy)-pentyl]-benzoic acid 5-cyano-5-(1-ethoxy-ethoxy)-1-methyl-pentyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4-Dimethoxy-6-[1-phenylsulfanyl-5-(toluene-4-sulfonyloxy)-pentyl]-benzoic acid 5-cyano-5-(1-ethoxy-ethoxy)-1-methyl-pentyl ester

There total 2 articles about 2,4-Dimethoxy-6-[1-phenylsulfanyl-5-(toluene-4-sulfonyloxy)-pentyl]-benzoic acid 5-cyano-5-(1-ethoxy-ethoxy)-1-methyl-pentyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-toluenesulfonyl chloride (98-59-9) → 2,4-Dimethoxy-6-[1-phenylsulfanyl-5-(toluene-4-sulfonyloxy)-pentyl]-benzoic acid 5-cyano-5-(1-ethoxy-ethoxy)-1-methyl-pentyl ester (84597-65-9)

Guidance literature:

Multi-step reaction with 2 steps

1: NaHSO₃

2: H₃O⁽¹⁺⁾

With oxonium; sodium hydrogensulfite;

DOI:10.1016/S0040-4039(00)85600-2

Reference yield:

2,4-Dimethoxy-6-[1-phenylsulfanyl-5-(toluene-4-sulfonyloxy)-pentyl]-benzoic acid 5-cyano-5-hydroxy-1-methyl-pentyl ester + ethyl vinyl ether (109-92-2,25104-37-4) → 2,4-Dimethoxy-6-[1-phenylsulfanyl-5-(toluene-4-sulfonyloxy)-pentyl]-benzoic acid 5-cyano-5-(1-ethoxy-ethoxy)-1-methyl-pentyl ester (84597-65-9)

Guidance literature:

With oxonium;

DOI:10.1016/S0040-4039(00)85600-2

Reference yield: 82.0%

2,4-Dimethoxy-6-[1-phenylsulfanyl-5-(toluene-4-sulfonyloxy)-pentyl]-benzoic acid 5-cyano-5-(1-ethoxy-ethoxy)-1-methyl-pentyl ester (84597-65-9) → 11-(1-Ethoxy-ethoxy)-2,4-dimethoxy-7-methyl-5-oxo-16-phenylsulfanyl-7,8,9,10,11,12,13,14,15,16-decahydro-5H-6-oxa-benzocyclotetradecene-11-carbonitrile (84574-16-3)

Guidance literature:

With sodium hexamethyldisilazane; In tetrahydrofuran; at 40 ℃; for 0.5h;

DOI:10.1016/S0040-4039(00)85600-2

upstream raw materials:

ethyl vinyl ether

p-toluenesulfonyl chloride

Downstream raw materials:

11-(1-Ethoxy-ethoxy)-2,4-dimethoxy-7-methyl-5-oxo-16-phenylsulfanyl-7,8,9,10,11,12,13,14,15,16-decahydro-5H-6-oxa-benzocyclotetradecene-11-carbonitrile

Zearalenone Dimethyl Ether

2,4-Dimethoxy-7-methyl-16-phenylsulfanyl-7,8,9,10,13,14,15,16-octahydro-12H-6-oxa-benzocyclotetradecene-5,11-dione

11-Hydroxy-2,4-dimethoxy-7-methyl-5-oxo-16-phenylsulfanyl-7,8,9,10,11,12,13,14,15,16-decahydro-5H-6-oxa-benzocyclotetradecene-11-carbonitrile