cis-2-(2-hydroxyethyl)-1-(p-tolylsulphonyl)-5-<(methylsulphonyl)acetyl>pyrrolidine

Base Information

Chemical Name:cis-2-(2-hydroxyethyl)-1-(p-tolylsulphonyl)-5-<(methylsulphonyl)acetyl>pyrrolidine
CAS No.:133038-55-8
Molecular Formula:C₁₆H₂₃NO₆S₂
Molecular Weight:389.494
Hs Code.:

Synonyms:cis-2-(2-hydroxyethyl)-1-(p-tolylsulphonyl)-5-<(methylsulphonyl)acetyl>pyrrolidine

Suppliers and Price of cis-2-(2-hydroxyethyl)-1-(p-tolylsulphonyl)-5-<(methylsulphonyl)acetyl>pyrrolidine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of cis-2-(2-hydroxyethyl)-1-(p-tolylsulphonyl)-5-<(methylsulphonyl)acetyl>pyrrolidine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of cis-2-(2-hydroxyethyl)-1-(p-tolylsulphonyl)-5-<(methylsulphonyl)acetyl>pyrrolidine

There total 9 articles about cis-2-(2-hydroxyethyl)-1-(p-tolylsulphonyl)-5-<(methylsulphonyl)acetyl>pyrrolidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 17609-14-2
methylsulphonylmethyl-lithium

: 133038-54-7
cis-5-(2-hydroxyethyl)-1-(p-tolylsulphonyl)proline ethyl ester

: 133038-55-8
cis-2-(2-hydroxyethyl)-1-(p-tolylsulphonyl)-5-<(methylsulphonyl)acetyl>pyrrolidine

Guidance literature:: In tetrahydrofuran; at -10 ℃; for 0.166667h;

Reference yield:

: 112009-90-2
ethyl 2-benzylideneaminohepta-5,6-dienoate

: 133038-55-8
cis-2-(2-hydroxyethyl)-1-(p-tolylsulphonyl)-5-<(methylsulphonyl)acetyl>pyrrolidine

Guidance literature:: Multi-step reaction with 7 steps

1: 59 percent / aq. HCl / diethyl ether / 0.67 h / Ambient temperature

2: CH₂Cl₂

3: 88 percent / AgBF₄ / CH₂Cl₂ / 72 h / Ambient temperature

4: CF₃CO₂H / CH₂Cl₂ / Ambient temperature

5: pyridine / 0 °C

6: 1) B₂H₆, 2) aq. NaOH, 30percent aq. H₂O₂ / 1) THF, 20 deg C, 20 min, 2) 30 min, room temp.

7: 63 percent / tetrahydrofuran / 0.17 h / -10 °C

With pyridine; hydrogenchloride; sodium hydroxide; dihydrogen peroxide; trifluoroacetic acid; diborane; silver tetrafluoroborate; In tetrahydrofuran; diethyl ether; dichloromethane;

Reference yield:

: 133038-46-7
ethyl 2-(methoxycarbonylamino)hepta-5,6-dienoate

: 133038-55-8
cis-2-(2-hydroxyethyl)-1-(p-tolylsulphonyl)-5-<(methylsulphonyl)acetyl>pyrrolidine

Guidance literature:: Multi-step reaction with 5 steps

1: 83 percent / AgBF₄ / CH₂Cl₂ / 65 h / Ambient temperature

2: NaI, (CH₃)3SiCl / acetonitrile / 2 h / Heating

3: pyridine / 0 °C

4: 1) B₂H₆, 2) aq. NaOH, 30percent aq. H₂O₂ / 1) THF, 20 deg C, 20 min, 2) 30 min, room temp.

5: 63 percent / tetrahydrofuran / 0.17 h / -10 °C

With pyridine; sodium hydroxide; chloro-trimethyl-silane; dihydrogen peroxide; sodium iodide; diborane; silver tetrafluoroborate; In tetrahydrofuran; dichloromethane; acetonitrile;