Technology Process of 2317157
There total 6 articles about 2317157 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium cyanoborohydride; acetic acid; N-ethyl-N,N-diisopropylamine;
In
methanol; dichloromethane;
DOI:10.1021/ml100306h
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: n-butyllithium / tetrahydrofuran / -78 °C
1.2: -78 °C
2.1: sodium carbonate / N,N-dimethyl-formamide / 90 °C
3.1: bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II); potassium carbonate / 1,4-dioxane; water / 80 °C
4.1: potassium tert-butylate; trimethylsulfoxonium iodide / tetrahydrofuran; dimethyl sulfoxide
5.1: sodium cyanoborohydride; acetic acid; N-ethyl-N,N-diisopropylamine / methanol; dichloromethane
With
n-butyllithium; bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II); potassium tert-butylate; trimethylsulfoxonium iodide; sodium cyanoborohydride; sodium carbonate; potassium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
3.1: Suzuki reaction / 4.1: Corey-Chaykovsky reaction;
DOI:10.1021/ml100306h
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: n-butyllithium / tetrahydrofuran / -78 °C
1.2: -78 °C
2.1: sodium carbonate / N,N-dimethyl-formamide / 90 °C
3.1: bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II); potassium carbonate / 1,4-dioxane; water / 80 °C
4.1: potassium tert-butylate; trimethylsulfoxonium iodide / tetrahydrofuran; dimethyl sulfoxide
5.1: sodium cyanoborohydride; acetic acid; N-ethyl-N,N-diisopropylamine / methanol; dichloromethane
With
n-butyllithium; bis(di-tert-?butyl(4-?dimethylaminophenyl)?phosphine)?dichloropalladium(II); potassium tert-butylate; trimethylsulfoxonium iodide; sodium cyanoborohydride; sodium carbonate; potassium carbonate; acetic acid; N-ethyl-N,N-diisopropylamine;
In
tetrahydrofuran; 1,4-dioxane; methanol; dichloromethane; water; dimethyl sulfoxide; N,N-dimethyl-formamide;
3.1: Suzuki reaction / 4.1: Corey-Chaykovsky reaction;
DOI:10.1021/ml100306h
