(1R,5R)-8-Methyl-8-azabicyclo[3.2.1]octan-3beta-ol

Base Information Edit

Chemical Name:(1R,5R)-8-Methyl-8-azabicyclo[3.2.1]octan-3beta-ol
CAS No.:120-29-6
Molecular Formula:C8H15NO
Molecular Weight:141.213
Hs Code.:29399990
European Community (EC) Number:204-384-2
Nikkaji Number:J840.392I
Wikipedia:Tropine
Wikidata:Q3540343
NCI Thesaurus Code:C61994
Mol file:120-29-6.mol

Synonyms:pseudotropine;tropine;tropine hydrobromide, (endo)-isomer;tropine hydrochloride, (endo)-isomer;tropine hydrochloride, (exo)-isomer;tropine, (exo)-isomer

Suppliers and Price of (1R,5R)-8-Methyl-8-azabicyclo[3.2.1]octan-3beta-ol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
Tropine
100g
$ 275.00

TCI Chemical
Tropine >98.0%(GC)(T)
5g
$ 14.00

TCI Chemical
Tropine >98.0%(GC)(T)
25g
$ 43.00

SynQuest Laboratories
Tropine 99%
500 g
$ 296.00

SynQuest Laboratories
Tropine 99%
100 g
$ 64.00

Sigma-Aldrich
Tropine ≥97.0% (NT)
50g
$ 139.00

Sigma-Aldrich
Tropine European Pharmacopoeia (EP) Reference Standard
$ 190.00

Sigma-Aldrich
Tropine European Pharmacopoeia (EP) Reference Standard
t2580300
$ 190.00

Sigma-Aldrich
Tropine ≥97.0% (NT)
10g
$ 46.90

Oakwood
Tropine 97%
25g
$ 18.00

Total 180 raw suppliers

Chemical Property of (1R,5R)-8-Methyl-8-azabicyclo[3.2.1]octan-3beta-ol Edit

Chemical Property:

Appearance/Colour:white to slightly yellow crystalline powder
Vapor Pressure:0.0106mmHg at 25°C
Melting Point:64 °C
Refractive Index:1.525
Boiling Point:232.999 °C at 760 mmHg
PKA:3.80(at 15℃)
Flash Point:112.5 °C
PSA：23.47000
Density:1.078 g/cm³
LogP:0.54180
Storage Temp.:2-8°C
Sensitive.:Hygroscopic
Solubility.:H2O: 0.1 g/mL, clear
Water Solubility.:100 g/L (20 ºC)
XLogP3:0.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:0
Exact Mass:141.115364102
Heavy Atom Count:10
Complexity:123

Purity/Quality:

99% ^*data from raw suppliers

Tropine ^*data from reagent suppliers

Safty Information:

Pictogram(s): Xi,Xn
Hazard Codes:Xi,Xn
Statements: 26/28-20/22
Safety Statements: 22-24/25

MSDS Files:: SDS file from LookChem

Useful:

Chemical Classes:Nitrogen Compounds -> Other Nitrogen Compounds
Canonical SMILES:CN1C2CCC1CC(C2)O
Isomeric SMILES:CN1[C@@H]2CC[C@@H]1CC(C2)O
Uses Tropine is an oxidative product of Tropane, used to synthesize alkaloid derivatives. Tropine as an oxidative product of Tropane, used to synthesize alkaloid derivatives. Benzatropine and etybenzatropine are derivatives of tropine. It is also a building block of atropine, an anticholinergic drug prototypical of the muscarinic antagonist class.

Technology Process of (1R,5R)-8-Methyl-8-azabicyclo[3.2.1]octan-3beta-ol

There total 62 articles about (1R,5R)-8-Methyl-8-azabicyclo[3.2.1]octan-3beta-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%