2-Benzyloxy-3-methoxy-6,beta-dinitrostyrene

Base Information

Chemical Name:2-Benzyloxy-3-methoxy-6,beta-dinitrostyrene
CAS No.:2426-62-2
Molecular Formula:C₁₆H₁₄N₂O₆
Molecular Weight:330.297
Hs Code.:
DSSTox Substance ID:DTXSID901182919

Synonyms:FIMFMXZSFUHXQJ-UHFFFAOYSA-N;DTXSID901182919;2-benzyloxy-3-methoxy-6,beta-dinitrostyrene;1-Methoxy-4-nitro-3-(2-nitroethenyl)-2-(phenylmethoxy)benzene

Suppliers and Price of 2-Benzyloxy-3-methoxy-6,beta-dinitrostyrene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-(Benzyloxy)-3-methoxy-β,6-dinitrostyrene
250mg
$ 1540.00

Medical Isotopes, Inc.
2-(Benzyloxy)-3-methoxy-β,6-dinitrostyrene
25 mg
$ 675.00

Total 5 raw suppliers

Chemical Property of 2-Benzyloxy-3-methoxy-6,beta-dinitrostyrene

Chemical Property:

Solubility.:DCM, Ethyl Acetate, Methanol
XLogP3:3.4
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:5
Exact Mass:330.08518617
Heavy Atom Count:24
Complexity:453

Purity/Quality:

99% ^*data from raw suppliers

2-(Benzyloxy)-3-methoxy-β,6-dinitrostyrene ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C(=C(C=C1)[N+](=O)[O-])C=C[N+](=O)[O-])OCC2=CC=CC=C2
Uses 2-(Benzyloxy)-3-methoxy-β,6-dinitrostyrene is an intermediate in the synthesis of 4-Hydroxymelatonin (H944635), a metabolite of Melatonin (M215000), a hormone found in animals that regulates sleep cycle.

Technology Process of 2-Benzyloxy-3-methoxy-6,beta-dinitrostyrene

There total 4 articles about 2-Benzyloxy-3-methoxy-6,beta-dinitrostyrene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

: 75-52-5
nitromethane

: 2426-61-1
2-(benzyloxy)-3-methoxy-6-nitrobenzaldehyde

: 2426-62-2
2-(benzyloxy)-1-methoxy-4-nitro-3-(2-nitrovinyl)benzene

Guidance literature:: nitromethane; With potassium carbonate; In 1,4-dioxane; at 20 ℃; for 0.166667h;

2-(benzyloxy)-3-methoxy-6-nitrobenzaldehyde; With 18-crown-6 ether; In 1,4-dioxane; for 24h;

With sodium acetate; acetic anhydride; In 1,4-dioxane; at 100 ℃;
DOI:10.1016/j.ejmech.2009.07.012

Reference yield:

: 2426-85-9
2-Hydroxy-3-methoxybenzaldehyde benzenesulfonate

: 2426-62-2
2-(benzyloxy)-1-methoxy-4-nitro-3-(2-nitrovinyl)benzene

Guidance literature:: Multi-step reaction with 3 steps

1: (i) NO₂/HNO₃, (ii) aq. KOH, MeOH

2: K₂CO₃ / dimethylformamide; dimethylsulfoxide

3: (i) aq. KOH, EtOH, (ii) NaOAc, Ac₂O

With potassium carbonate; In dimethyl sulfoxide; N,N-dimethyl-formamide;

Reference yield:

: 100-44-7
benzyl chloride

: 2426-62-2
2-(benzyloxy)-1-methoxy-4-nitro-3-(2-nitrovinyl)benzene

Guidance literature:: Multi-step reaction with 2 steps

1: K₂CO₃ / dimethylformamide; dimethylsulfoxide

2: (i) aq. KOH, EtOH, (ii) NaOAc, Ac₂O

With potassium carbonate; In dimethyl sulfoxide; N,N-dimethyl-formamide;