2-Benzyloxy-3-Methoxy-6-nitrobenzaldehyde

Base Information

Chemical Name:2-Benzyloxy-3-Methoxy-6-nitrobenzaldehyde
CAS No.:2426-61-1
Molecular Formula:C₁₅H₁₃NO₅
Molecular Weight:287.272
Hs Code.:
Mol file:2426-61-1.mol

Synonyms:2-(benzyloxy)-3-methoxy-6-nitrobenzaldehyde

Suppliers and Price of 2-Benzyloxy-3-Methoxy-6-nitrobenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Benzyloxy-3-methoxy-6-nitrobenzaldehyde
25mg
$ 165.00

Medical Isotopes, Inc.
2-Benzyloxy-3-methoxy-6-nitrobenzaldehyde
250 mg
$ 2200.00

Total 5 raw suppliers

Chemical Property of 2-Benzyloxy-3-Methoxy-6-nitrobenzaldehyde

Chemical Property:

Solubility.:DCM, Ethyl Acetate, Methanol

Purity/Quality:

99% ^*data from raw suppliers

2-Benzyloxy-3-methoxy-6-nitrobenzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Uses 2-Benzyloxy-3-methoxy-6-nitrobenzaldehyde is an intermediate in the synthesis of 4-Hydroxymelatonin (H944635), a metabolite of Melatonin (M215000), a hormone found in animals that regulates sleep cycle.

Technology Process of 2-Benzyloxy-3-Methoxy-6-nitrobenzaldehyde

There total 4 articles about 2-Benzyloxy-3-Methoxy-6-nitrobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 100-39-0
benzyl bromide

: 111042-36-5
2-Hydroxy-3-methoxy-6-nitrobenzaldehyde, sodium salt

: 2426-61-1
2-(benzyloxy)-3-methoxy-6-nitrobenzaldehyde

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; acetonitrile; at 100 ℃; for 4h;
DOI:10.1021/ol051286l DOI:10.1021/jo701987r

Reference yield: 90.0%

: 2426-86-0
2-hydroxy-3-methoxy-6-nitrobenzaldehyde

: 100-44-7
benzyl chloride

: 2426-61-1
2-(benzyloxy)-3-methoxy-6-nitrobenzaldehyde

Guidance literature:: 2-hydroxy-3-methoxy-6-nitrobenzaldehyde; With potassium carbonate; In acetonitrile; at 20 ℃; for 0.166667h;

benzyl chloride; With potassium iodide; In acetonitrile; for 2.5h; Reflux;
DOI:10.1016/j.ejmech.2009.07.012

Reference yield:

: 2426-85-9
2-Hydroxy-3-methoxybenzaldehyde benzenesulfonate

: 2426-61-1
2-(benzyloxy)-3-methoxy-6-nitrobenzaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1: (i) NO₂/HNO₃, (ii) aq. KOH, MeOH

2: K₂CO₃ / dimethylformamide; dimethylsulfoxide

With potassium carbonate; In dimethyl sulfoxide; N,N-dimethyl-formamide;