6,7-dimethoxy-3-(4-isopropyloxy-3-methoxyphenyl)-2-methyl-4-(2-oxoethyl)isoquinolinium iodide

Base Information

Chemical Name:6,7-dimethoxy-3-(4-isopropyloxy-3-methoxyphenyl)-2-methyl-4-(2-oxoethyl)isoquinolinium iodide
CAS No.:1392399-38-0
Molecular Formula:C₂₄H₂₈NO₅*I
Molecular Weight:537.395
Hs Code.:

Synonyms:6,7-dimethoxy-3-(4-isopropyloxy-3-methoxyphenyl)-2-methyl-4-(2-oxoethyl)isoquinolinium iodide

Suppliers and Price of 6,7-dimethoxy-3-(4-isopropyloxy-3-methoxyphenyl)-2-methyl-4-(2-oxoethyl)isoquinolinium iodide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 6,7-dimethoxy-3-(4-isopropyloxy-3-methoxyphenyl)-2-methyl-4-(2-oxoethyl)isoquinolinium iodide

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 6,7-dimethoxy-3-(4-isopropyloxy-3-methoxyphenyl)-2-methyl-4-(2-oxoethyl)isoquinolinium iodide

There total 4 articles about 6,7-dimethoxy-3-(4-isopropyloxy-3-methoxyphenyl)-2-methyl-4-(2-oxoethyl)isoquinolinium iodide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 1392399-36-8
6,7-dimethoxy-3-(4-isopropyloxy-3-methoxyphenyl)-4-(2-oxoethyl)isoquinoline

: 74-88-4
methyl iodide

: 1392399-38-0
6,7-dimethoxy-3-(4-isopropyloxy-3-methoxyphenyl)-2-methyl-4-(2-oxoethyl)isoquinolinium iodide

Guidance literature:: In dichloromethane; at 20 ℃; for 24h;
DOI:10.1016/j.bmc.2012.05.061

Reference yield:

: 5392-10-9
2-bromo-4,5-dimethoxybenzaldehyde

: 1392399-38-0
6,7-dimethoxy-3-(4-isopropyloxy-3-methoxyphenyl)-2-methyl-4-(2-oxoethyl)isoquinolinium iodide

Guidance literature:: Multi-step reaction with 4 steps

1: 20 °C

2: dibromo[1,2-bis(diphenylphosphino)ethane]nickel(II); zinc / acetonitrile / Reflux

3: oxalyl dichloride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine / dichloromethane / -78 °C

4: dichloromethane / 24 h / 20 °C

With oxalyl dichloride; dibromo[1,2-bis(diphenylphosphino)ethane]nickel(II); dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine; zinc; In dichloromethane; acetonitrile; 3: Swern oxidation;
DOI:10.1016/j.bmc.2012.05.061

Reference yield:

: 138505-27-8
4-bromo-1-isopropoxy-2-methoxy-benzene

: 1392399-38-0
6,7-dimethoxy-3-(4-isopropyloxy-3-methoxyphenyl)-2-methyl-4-(2-oxoethyl)isoquinolinium iodide

Guidance literature:: Multi-step reaction with 4 steps

1: copper(l) iodide; bis-triphenylphosphine-palladium(II) chloride; diisopropylamine / Reflux

2: dibromo[1,2-bis(diphenylphosphino)ethane]nickel(II); zinc / acetonitrile / Reflux

3: oxalyl dichloride; dimethyl sulfoxide; N-ethyl-N,N-diisopropylamine / dichloromethane / -78 °C

4: dichloromethane / 24 h / 20 °C

With bis-triphenylphosphine-palladium(II) chloride; copper(l) iodide; oxalyl dichloride; dibromo[1,2-bis(diphenylphosphino)ethane]nickel(II); dimethyl sulfoxide; diisopropylamine; N-ethyl-N,N-diisopropylamine; zinc; In dichloromethane; acetonitrile; 1: Sonogashira coupling / 3: Swern oxidation;
DOI:10.1016/j.bmc.2012.05.061